Evidence map›Paper›PMID 25407631›Full record

ArticleBMC complementary and alternative medicine2014

Evaluation of the cytotoxicity and phototoxicity of Caryocar brasiliense supercritical carbon dioxide extract.

Lilian F B Amaral, Patricia Moriel, Mary Ann Foglio, Priscila G Mazzola

Abstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lilian F B AmaralDepartment of Clinical Pathology, Faculty of Medical Sciences, University of Campinas (FCM-UNICAMP), Rua Tessália Vieira de Camargo, 126 Campinas, SP, Brasil. liufbarbosa@yahoo.com.br.
Patricia Moriel
Mary Ann Foglio
Priscila G Mazzola

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaryocar brasiliense Camb (Pequi) is a typical Brazilian Cerrado fruit tree. Its fruit is used as a vitamin source for culinary purposes and as a source of oil for the manufacture of cosmetics. C. brasiliense supercritical CO2 extracts exhibit antimicrobial activity against the bacteria Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus and also possess antioxidant activity. This study was designed to evaluate the in vitro cytotoxicity and phototoxicity of the supercritical CO2 extract obtained from the leaves of this species.

methodsIn vitro cytotoxicity and phototoxicity of C. brasiliense supercritical CO2 extracts were assessed using a tetrazolium-based colorimetric assay (XTT) and Neutral Red methods.

resultsWe found that the C. brasiliense (Pequi) extract obtained by supercritical CO2 extraction did not present cytotoxic and phototoxic hazards.

conclusionsThis finding suggests that the extract may be useful for the development of cosmetic and/or pharmaceutical products.

Indexed as

Plant Leaves3T3 CellsAnimalsAnti-Bacterial AgentsBacteriaBrazilEricalesFibroblastsFruitMicePlant ExtractsAnti-Bacterial AgentsPlant Extracts

Identifiers

PMID25407631
PMCPMC4255682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.