ArticleThe international journal of cardiovascular imaging2015
Analysis of coronary arterial calcification components with coronary CT angiography using single-source dual-energy CT with fast tube voltage switching.
Article in The international journal of cardiovascular imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Applicability of Effective Atomic Number (Zeff) Image Analysis of Coronary Plaques Measured With Photon- Counting Computed Tomography.Investigative radiology · 2025Article
- Spectral optimization using fast kV switching and filtration for photon counting CT with realistic detector responses: a simulation study.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Serum oxalate concentration is associated with coronary artery calcification and cardiovascular events in Japanese dialysis patients.Scientific reports · 2023Article
- Dual-energy CT plaque characteristics of post mortem thin-cap fibroatheroma in comparison to infarct-related culprit lesions.Heart and vessels · 2022Article
- An Overview of X-ray Photon Counting Spectral Imaging (x-CSI) with a Focus on Gold Nanoparticle Quantification in Oncology.Journal of imaging · 2021Review
- Plasma Oxalate Concentration and Patients With CKD.Kidney international reports · 2021Article
- Metal artifact reduction and tumor detection using photon-counting multi-energy computed tomography.PloS one · 2021Article
- Dual-energy computed tomography using a gantry-based preclinical cone-beam microcomputed tomography scanner.Journal of medical imaging (Bellingham, Wash.) · 2018Article
- Fluorescent angioscopic imaging of calcium phosphate tribasic: precursor of hydroxyapatite, the major calcium deposit in human coronary plaques.The international journal of cardiovascular imaging · 2017Article
- Cardiovascular imaging 2014 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2015Review
- Improved Calcium Scoring at Dual-Energy Computed Tomography Angiography Using a High-Z Contrast Element and Novel Material Separation Technique.Journal of computer assisted tomographyArticle
- Calcium orthophosphates (CaPOProgress in biomaterialsArticle
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Authors and funding
7 authors.
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Abstract
Clinical cardiac applications of single-source dual-energy computed tomography (DECT) have recently been introduced. This study aimed to analyze the components of coronary arterial calcification (CAC) in vivo by material decomposition achieved with DECT. We reconstructed computed tomography (CT) angiography images for 51 consecutive patients with CACs who had undergone electrocardiography-gated coronary CT angiography by single-source DECT with fast tube voltage switching. We placed regions of interest (ROIs) within the CAC with margins of at least 0.5 mm to minimize partial volume averaging. We compared histograms for the effective atomic number (EAN) and the median, mean, and maximum EANs for each CAC with the theoretical EANs for possible CAC components, including hydroxyapatite (HA), calcium oxalate monohydrate (COM), and dicalcium phosphate dehydrate. We also investigated the in vivo EAN for COM and in vitro EAN for HA by our phantom experiment. Analysis of the CAC components was feasible in 177 ROIs from 28 patients. The median EAN was 13.8 ± 0.8 (95% confidence interval 13.7-13.9), which is similar to the theoretical EAN for COM (13.8). The EAN for HA in vitro was 16.5 ± 0.1, which was slightly higher than the theoretical EAN value for HA (16.1). Notably, the median EAN in 144 ROIs (81.4%) was between 11.2 and 14.4, which is the reported range of the in vivo EAN for COM. Our results suggest that COM might be a more frequent CAC component than previously reported.
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