ArticleParasitology research2015
ATP synthase: an identified target gene of bantam in paired female Schistosoma japonicum.
Article in Parasitology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Roles of microRNAs and Long Non-Coding RNAs Encoded by Parasitic Helminths in Human Carcinogenesis.International journal of molecular sciences · 2022Review
- Comparative analysis of microRNA expression profiles of adult Schistosoma japonicum isolated from water buffalo and yellow cattle.Parasites & vectors · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) are a class of small non-coding RNAs that function in transcriptional and post-transcriptional regulation of gene expression. An increasing number of schistosome miRNAs have been identified and are expected possibly involved in differentiation, development, and metabolism. However, limited information is available concerning the target genes of schistosome miRNAs. In the present study, the key target genes of bantam, an abundant miRNA found in paired female Schistosoma japonicum, were predicted by bioinformatics analysis and Solexa technology. Luciferase reporter assay and bantam mimic assay were applied in combination to further verify the targets of bantam. Results showed that ATP synthase (CAX76793.1), one of the three selected predicted targets, was confirmed as the target of bantam; bantam mimic assay results also showed that the two other predicted targets, namely, ataxia telangiectasia mutated (ATM)-related (XP_002571630.1), and ribosomal protein L30 (CAX72575.1), were not confirmed as targets. This research proposed the design and significance of reasonable biological experiments that could be performed to identify miRNA target genes in schistosomes.
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Registered trials
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