ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2015
Endorectal ultrasonography, strain elastography and MRI differentiation of rectal adenomas and adenocarcinomas.
Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed.
- Minimally Invasive Bowel Cancer Detection through Vibrating Microrobot-Induced Elastography.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2025Article
- Endorectal ultrasound with elastography for differentiating benign and malignant rectal tumors: a systematic review and meta-analysis.American journal of translational research · 2025Review
- Application of cellular microstructural diffusion MRI (cell size imaging) in rectal lesions: a preliminary study.Frontiers in oncology · 2025Article
- Elastography of the Male Pelvic Region-Perspectives on Malignant Lesions.Diagnostics (Basel, Switzerland) · 2024Review
- Endoscopic Submucosal Dissection, Endoscopic Mucosal Resection, and Transanal Minimally Invasive Surgery for the Management of Rectal and Anorectal Lesions: A Narrative Review.Journal of clinical medicine · 2023Review
- Endoscopic Ultrasound (EUS) Guided Elastography.Diagnostics (Basel, Switzerland) · 2023Review
- A model based on endorectal ultrasonography predicts lateral lymph node metastasis in low and middle rectal cancer.Journal of clinical ultrasound : JCU · 2022Article
- Article
- Can Ultrasound Elastography Discriminate between Rectal Adenoma and Cancer? A Systematic Review.Cancers · 2021Review
- Indications and outcomes of endoscopic resection for non-pedunculated colorectal lesions: A narrative review.World journal of gastrointestinal endoscopy · 2021Review
- Adding trans-abdominal elastography to the diagnostic tool for an ileal gastrointestinal stromal tumor: a case report.BMC medical imaging · 2019Article
- Rectal Endoscopic Ultrasound in Clinical Practice.Current gastroenterology reports · 2019Review
- EFSUMB Recommendations for Gastrointestinal Ultrasound Part 3: Endorectal, Endoanal and Perineal Ultrasound.Ultrasound international open · 2019Review
- Strain Elastography - How To Do It?Ultrasound international open · 2017Review
- Endoscopic ultrasound in oncology: An update of clinical applications in the gastrointestinal tract.World journal of gastrointestinal endoscopy · 2017Review
- Non-invasive evaluation of intestinal disorders: The role of elastographic techniques.World journal of gastroenterology · 2017Review
- Maximizing the endosonography: The role of contrast harmonics, elastography and confocal endomicroscopy.World journal of gastroenterology · 2017Review
- Optimal Imaging Strategies for Rectal Cancer Staging and Ongoing Management.Current treatment options in oncology · 2016Review
- Advances in endoscopic ultrasound imaging of colorectal diseases.World journal of gastroenterology · 2016Review
- EUS elastography: How to do it?Endoscopic ultrasoundArticle
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Abstract
aimStrain elastography is a method for recording tissue hardness. Strain in different areas may be compared using strain ratio (SR). The aims of this study were to validate a previously proposed SR cut-off value of 1.25 for differentiating adenocarcinomas from adenomas and to compare the performance of endorectal ultrasonography (ERUS), strain elastography and MRI in the same patients.
methodA prospective evaluation of 120 consecutive patients with rectal neoplasia, using a predetermined elastography strain ratio cut-off value, was performed to differentiate adenomas from adenocarcinomas. ERUS and MRI were performed according to standard routine at Haukeland University Hospital, defining T0 as adenomas and T1-T4 as adenocarcinomas. Subsequent histopathology was used as the reference standard.
resultsHistopathological evaluation revealed 21 adenomas and 99 adenocarcinomas. Sensitivity, specificity and accuracy (with 95% CI) were as follows: ERUS: 0.96 (0.90-0.99), 0.62 (0.40-0.80) and 0.90 (0.83-0.94); elastography SR: 0.96 (0.90-0.99), 0.86 (0.66-0.96) and 0.94 (0.88-0.97); and MRI: 0.99 (0.94-1.00), 0.07 (0.00-0.31) and 0.87 (0.80-0.93).
conclusionThis study confirms that the elastography SR assessment accurately differentiates sessile adenomas from adenocarcinomas. SR assessment has a superior ability to differentiate adenomas and adenocarcinomas when compared with ERUS and MRI. MRI examination seems unable to recognize adenomas and should be interpreted with care when early-stage rectal neoplasia is suspected.
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