ArticleScandinavian journal of trauma, resuscitation and emergency medicine2014
Increased risk of ischemic stroke in patients with mild traumatic brain injury: a nationwide cohort study.
Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Risk of stroke after traumatic brain injury: a systematic review and meta-analysis.Acta neurologica Belgica · 2025Pooled it
- Traumatic Brain Injury Is Associated With Both Hemorrhagic Stroke and Ischemic Stroke: A Systematic Review and Meta-Analysis.Frontiers in neuroscience · 2022Pooled it
- Stroke risk following traumatic brain injury: Systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2021Pooled it
- Systematic Review of Sex and Gender Effects in Traumatic Brain Injury: Equity in Clinical and Functional Outcomes.Frontiers in neurology · 2021Pooled it
- Mapping the Evidence on Cardiovascular Disease Risk among Individuals Experiencing Disability: A Scoping Review.American journal of physical medicine & rehabilitation · 2026Article
- Traumatic brain injury persistently increases the incidence of both ischemic and hemorrhagic strokes: Potential mechanisms.Progress in neurobiology · 2025Review
- Association Between Stroke and Traumatic Brain Injury: A Systematic Review and Meta-Analysis.NeuroSci · 2025Review
- Article
- Prevalence and characteristics of comorbid stroke and traumatic brain injury in a real-world population: findings from a nationally representative cross-sectional survey in China.BMC public health · 2023Article
- Article
- Long-Term Risk of Stroke after Traumatic Brain Injury: A Population-Based Medical Record Review Study.Neuroepidemiology · 2022Article
- Article
- Increased Risk of Stroke in Patients of Concussion: A Nationwide Cohort Study.International journal of environmental research and public health · 2017Article
- Effect of glycemic control on the risk of pancreatic cancer: A nationwide cohort study.Medicine · 2016Article
- Increased risk of ischemic stroke in patients with burn injury: a nationwide cohort study in Taiwan.Scandinavian journal of trauma, resuscitation and emergency medicine · 2016Article
- Traumatic Brain Injury and Substance Related Disorder: A 10-Year Nationwide Cohort Study in Taiwan.Neural plasticity · 2016Article
- Bidirectional Relationship Between Diabetes and Acute Pancreatitis: A Population-Based Cohort Study in Taiwan.Medicine · 2016Article
- End-tidal carbon dioxide monitoring may be associated with a higher possibility of return of spontaneous circulation during out-of-hospital cardiac arrest: a population-based study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is known that the risk of stroke in patients with traumatic brain injury might be increased. However, the relationship between mild traumatic brain injury and ischemic stroke has never been established. We conducted a study of patients in Taiwan with mild traumatic brain injury to evaluate if they had a higher risk of stroke compared with the general population.
methodsWe utilized a sampled National Health Insurance claims database containing one million beneficiaries. We followed all adult beneficiaries older than 18 years from January 1, 2007 to December 31, 2010 to determine if they were diagnosed with ischemic stroke. We further identified patients with mild traumatic brain injury and compared their risk of ischemic stroke with the general population.
resultsWe identified 24,905 patients with mild traumatic brain injury and 719,811 patients without mild traumatic brain injury. After controlling for age, gender, urbanization level, socioeconomic status, diabetes, hypertension, coronary artery disease, hyperlipidemia, history of alcohol intoxication, malignancies, heart failure, atrial fibrillation, smoking, obesity, epilepsy, peripheral artery disease and Charlson Comorbidity Index score, the adjusted hazard ratio for ischemic stroke was 1.46 (95% confidence interval, 1.33-1.62).
conclusionMild traumatic brain injury is an independent significant risk factor for ischemic stroke.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.