ArticleeLife2014
Intercollicular commissural connections refine the representation of sound frequency and level in the auditory midbrain.
Article in eLife, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Rethinking hierarchy: the auditory system as an integrated cortical-subcortical network.Nature reviews. Neuroscience · 2026Review
- Binaural Processing Deficits in Autism Spectrum Disorder.Audiology research · 2026Review
- Functional MRI reveals subcortical auditory push-pull interactions requiring intercollicular integrity.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Neurotransmitter phenotype and axonal projection patterns of VIP-expressing neurons in the inferior colliculus.Journal of chemical neuroanatomy · 2022Article
- Bilateral Interactions in the Mouse Dorsal Inferior Colliculus Enhance the Ipsilateral Neuronal Responses and Binaural Hearing.Frontiers in physiology · 2022Article
- Integrative Treatment for Tinnitus Combining Repeated Facial and Auriculotemporal Nerve Blocks With Stimulation of Auditory and Non-auditory Nerves.Frontiers in neuroscience · 2022Article
- Inhibitory NPY Neurons Provide a Large and Heterotopic Commissural Projection in the Inferior Colliculus.Frontiers in neural circuits · 2022Article
- Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices.Neural plasticity · 2021Article
- Subtypes of GABAergic cells in the inferior colliculus.Hearing research · 2019Review
- A novel class of inferior colliculus principal neurons labeled in vasoactive intestinal peptide-Cre mice.eLife · 2019Article
- Puncta of Neuronal Nitric Oxide Synthase (nNOS) Mediate NMDA Receptor Signaling in the Auditory Midbrain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Noise Trauma-Induced Behavioral Gap Detection Deficits Correlate with Reorganization of Excitatory and Inhibitory Local Circuits in the Inferior Colliculus and Are Prevented by Acoustic Enrichment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Compensating Level-Dependent Frequency Representation in Auditory Cortex by Synaptic Integration of Corticocortical Input.PloS one · 2017Article
- Responses from two firing patterns in inferior colliculus neurons to stimulation of the lateral lemniscus dorsal nucleus.Neural regeneration research · 2016Article
- Commissural Gain Control Enhances the Midbrain Representation of Sound Location.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Connections unifying hemispheric sensory representations of vision and touch occur in cortex, but for hearing, commissural connections earlier in the pathway may be important. The brainstem auditory pathways course bilaterally to the inferior colliculi (ICs). Each IC represents one side of auditory space but they are interconnected by a commissure. By deactivating one IC in guinea pig with cooling or microdialysis of procaine, and recording neural activity to sound in the other, we found that commissural input influences fundamental aspects of auditory processing. The areas of nonV frequency response areas (FRAs) were modulated, but the areas of almost all V-shaped FRAs were not. The supra-threshold sensitivity of rate level functions decreased during deactivation and the ability to signal changes in sound level was decremented. This commissural enhancement suggests the ICs should be viewed as a single entity in which the representation of sound in each is governed by the other.
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Registered trials
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