ReviewCurrent opinion in pulmonary medicine2015
The respiratory microbiome and innate immunity in asthma.
Review in Current opinion in pulmonary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Effects of probiotics, prebiotics, synbiotics and postbiotics on pediatric asthma: a systematic review.Frontiers in nutrition · 2025Pooled it
- Chronic Inflammation as the Underlying Mechanism of the Development of Lung Diseases in Psoriasis: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Article
- Labor Status at Delivery and Lung Function in Extremely Prematurely Born Young Adults.Pediatric pulmonology · 2025Article
- Allergic Sensitization Driving Immune Phenotyping and Disease Severity in a Mouse Model of Asthma.Allergy, asthma & immunology research · 2023Article
- Micrococcus luteus-derived extracellular vesicles attenuate neutrophilic asthma by regulating miRNAs in airway epithelial cells.Experimental & molecular medicine · 2023Article
- Comparison of the respiratory bacterial microbiome in cats with feline asthma and chronic bronchitis.Frontiers in veterinary science · 2023Article
- Association of asthma and herpes zoster, the role of vaccination: A literature review.Immunity, inflammation and disease · 2022Review
- Alterations in the respiratory tract microbiome in COVID-19: current observations and potential significance.Microbiome · 2022Review
- Ocular surface disturbance in patients after acute COVID-19.Clinical & experimental ophthalmology · 2022Article
- Future Prospect of Oral Microbiota Influencing Allergy/Asthma Development.Frontiers in microbiology · 2022Article
- Respiratory dysbiosis in cats with spontaneous allergic asthma.Frontiers in veterinary science · 2022Article
- Microbial regulation of offspring diseases mediated by maternal-associated microbial metabolites.Frontiers in microbiology · 2022Review
- Impact of Probiotic Bacteria on Respiratory Allergy Disorders.Frontiers in microbiology · 2021Review
- Species-level evaluation of the human respiratory microbiome.GigaScience · 2020Article
- Asthma increases the risk of herpes zoster: a nested case-control study using a national sample cohort.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020Article
- The Role of the Microbiome in Asthma: The Gut⁻Lung Axis.International journal of molecular sciences · 2018Review
- Effect of clinical parameters on the ocular surface microbiome in children and adults.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
- Lung Microbiota and Its Impact on the Mucosal Immune Phenotype.Microbiology spectrum · 2017Review
- Effect of TiO₂ Nanoparticles on Inflammasome-Mediated Airway Inflammation and Responsiveness.Allergy, asthma & immunology research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purpose of reviewThe purpose of this study is to summarize recent studies of the lower respiratory microbiome in asthma, the role of innate immunity in asthma and strategies to understand complex microbiome-immune interactions in asthma. RECENT
findingsRecent evidence indicates that the composition of lower respiratory microbiota in asthmatic individuals, across a spectrum of disease severity, is altered compared with healthy individuals. Attributes of this altered airway microbiome have been linked to clinical and inflammatory features of asthma. The importance of innate immune cells and mucosal defense systems in asthma is increasingly appreciated and may be dysregulated in the disease. SUMMARY: Interactions between the respiratory microbiome and innate mucosal immunity in asthma are complex and a challenge to dissect. Multiple avenues of investigation, leveraging a variety of methodologies, will need to be pursued to understand functional relationships to clinical and inflammatory phenotypes seen in asthma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.