ReviewAnnals of translational medicine2014
Galectins as therapeutic targets for hematological malignancies: a hopeful sweetness.
Abstract readReview
In one paragraph
Review in Annals of translational medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Tandem-repeat lectins: structural and functional insights.Glycobiology · 2024Pooled it
- Drug resistance in chronic myeloid leukemia: the involvement of Galectin-1 and Galectin-3.Molecular biology reports · 2026Review
- Article
- Transcriptome Analysis of Diffuse Large B-Cell Lymphoma Cells Inducibly Expressing MyD88 L265P Mutation Identifies Upregulated CD44, LGALS3, NFKBIZ, and BATF as Downstream Targets of Oncogenic NF-κB Signaling.International journal of molecular sciences · 2023Article
- Promoter methylation might shift the balance of Galectin-3 & 12 expression inFrontiers in genetics · 2023Article
- Galectins dysregulation: A way for cancer cells to invade and pervade.Oncology research · 2022Article
- Immunomodulatory effects of galectin-1 in patients with chronic lymphocytic leukemia.Central-European journal of immunology · 2021Article
- Prognostic Value of Galectin-9 Relates to Programmed Death-Ligand 1 in Patients With Multiple Myeloma.Frontiers in oncology · 2021Article
- Increased serum levels of Galectin-9 in patients with chronic lymphocytic leukemia.Oncology letters · 2019Article
- Review
- Role of Galectins in Multiple Myeloma.International journal of molecular sciences · 2017Review
- Eviction from the sanctuary: Development of targeted therapy against cell adhesion molecules in acute lymphoblastic leukemia.Seminars in oncology · 2017Review
- Galectin-3, histone deacetylases, and Hedgehog signaling: Possible convergent targets in schistosomiasis-induced liver fibrosis.PLoS neglected tropical diseases · 2017Review
- Galectin-9: From cell biology to complex disease dynamics.Journal of biosciences · 2016Review
- The emerging roles of exosomes in leukemogeneis.Oncotarget · 2016Review
- How to avoid being eaten: a lymphoma's defense.Blood · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 1 institution in 1 country.
Camilo Pena1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Leonardo Mirandola1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Jose A Figueroa1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Nattamol Hosiriluck1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Natallia Suvorava1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Kayley Trotter1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Adair Reidy1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Rahman Rakhshanda1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Drew Payne1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Marjorie Jenkins1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Fabio Grizzi1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Lauren Littlefield1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Maurizio Chiriva-Internati1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Everardo Cobos1 Department of Internal Medicine at the Division of Hematology & Oncology, Texas Tech University Health Sciences Center, Lubbock, TX, USA ; 2 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 3 Kiromic LLC, TX, USA ; 4 Division of Surgical Oncology, Texas Tech University Medical Center, Amarillo, TX, USA ; 5 Laura W. Bush Institute for Women's Health and Center for Women's Health and Gender-Based Medicine, Amarillo, TX, USA ; 6 Humanitas Clinical and Research Center, Milan, Italy.
Texas Tech University · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
Galectins are family of galactose-binding proteins known to play critical roles in inflammation and neoplastic progression. Galectins facilitate the growth and survival of neoplastic cells by regulating their cross-talk with the extracellular microenvironment and hampering anti-neoplastic immunity. Here, we review the role of galectins in the biology of hematological malignancies and their promise as potential therapeutic agents in these diseases.
Indexed as
galectin-3 (Gal-3)Galectinsleukemialymphomasmultiple myeloma (MM)
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.