Evidence map›Paper›PMID 25405132›Full record

ArticleMedical journal of the Islamic Republic of Iran2014

Oral magnesium supplementation in type II diabetic patients.

Mehrdad Solati, Elham Ouspid, Saeedeh Hosseini, Nepton Soltani, Mansoor Keshavarz, Mohsen Dehghani

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PubMed Full text at PMC
In one paragraph

Article in Medical journal of the Islamic Republic of Iran, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 10 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 10 syntheses or guidelines pooled it, 71 citations in OpenAlex.

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  16. Exploring the mechanisms connecting the sympathetic nervous system and type 2 diabetes: Focus on renal denervation.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mehrdad Solati1. Assistant Professor (Endocrinologist), Department of Internal Medicine and Endocrinology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. msolati@hums.ac.ir.
Elham Ouspid2. MD, General practitioner, Department of Internal Medicine, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. elhamouspid@yahoo.com.
Saeedeh Hosseini3. MD, General practitioner, Department of Internal Medicine, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. drsaideh@gmail.com.
Nepton Soltani4. PhD, Associated Professor, Department of Physiology, Faculty of medicine, Hormozgan University of Medical Sciences and Cardiovascular Research Center for Hormozgan University of Medical Sciences, Bandar Abbas, Iran. neptun.soltani@gmail.com , nsoltani@hums.ac.ir.
Mansoor Keshavarz5. MD, PhD, Professor, Department of Physiology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohsen Dehghani6. Assistant Professor (Pathologist), Department of Pathology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran. mdehghanei@hums.ac.ir.
Hormozgan University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnesium is the second most abundant intracellular cation. It plays an important role in insulin homeostasis and glucose metabolism through multiple enzymatic reactions. With increasing data on magnesium deficiency in diabetic patients and epidemiological studies demonstrating magnesium deficiency as a risk factor for diabetes, it is logical to search for its possible beneficial effects on diabetes control and prevention. We aimed to determine whether oral magnesium supplementation improves metabolic control, lipid profile and blood pressure in patients with type II diabetes.

methodsFifty four patients with type II diabetes were included in a randomized double blind placebocontrolled clinical trial.Patients received either placebo or 300 mg elemental magnesium (as magnesium sulfate -MgSo4-) daily, for 3 months. Metabolic control, lipid profile, blood pressure, magnesium status, hepatic enzymes, hemoglobin concentration, and anthropometric indices were determined in the beginning and at the end of the study.

resultsDaily administration of 300 mg elemental magnesium for 3 months, significantly improved fasting blood glucose (183.9±15.43 to 125.8±6.52 vs. 196.5±28.12 to 136.5±7.94, p< 0.0001), 2-hour post prandial glucose (239.1±74.75 to 189.1±60mg/dl vs. 246.4±97.37 to 247.8±86.74mg/dl, p< 0.01), lipid profile, blood pressure and hepatic enzymes.

conclusionOral magnesium supplementation with proper dosage has beneficial effects on blood glucose, lipid profile, and blood pressure in patients with type II diabetes.

Indexed as

Blood glucoseBlood pressureDiabetesLipid profileMagnesium

Identifiers

PMID25405132
PMCPMC4219896
OpenAlexW1765299770

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.