Evidence map›Paper›PMID 25405095›Full record

ReviewWorld journal of orthopedics2014

Metallic debris from metal-on-metal total hip arthroplasty regulates periprosthetic tissues.

Christoph H Lohmann, Gurpal Singh, Hans-Georg Willert, Gottfried H Buchhorn

Abstract readReview
In one paragraph

Review in World journal of orthopedics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Vitamin D deficiency in early implant failure: two case reports.International journal of implant dentistry · 2016
    Article
  10. Article
  11. Article
  12. Cystic lesion around the hip joint.World journal of orthopedics · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christoph H LohmannChristoph H Lohmann, Gurpal Singh, Department of Orthopaedic Surgery, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Gurpal SinghChristoph H Lohmann, Gurpal Singh, Department of Orthopaedic Surgery, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Hans-Georg WillertChristoph H Lohmann, Gurpal Singh, Department of Orthopaedic Surgery, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Gottfried H BuchhornChristoph H Lohmann, Gurpal Singh, Department of Orthopaedic Surgery, Otto-von-Guericke University, 39120 Magdeburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The era of metal-on-metal (MoM) total hip arthroplasty has left the orthopaedic community with valuable insights and lessons on periprosthetic tissue reactions to metallic debris. Various terms have been used to describe the tissue reactions. Sometimes the nomenclature can be confusing. We present a review of the concepts introduced by Willert and Semlitsch in 1977, along with further developments made in the understanding of periprosthetic tissue reactions to metallic debris. We propose that periprosthetic tissue reactions be thought of as (1) gross (metallosis, necrosis, cyst formation and pseudotumour); (2) histological (macrophage-dominated, lymphocyte-dominated or mixed); and (3) molecular (expression of inflammatory mediators and cytokines such as interleukin-6 and tumor necrosis factor-alpha). Taper corrosion and modularity are discussed, along with future research directions to elucidate the antigen-presenting pathways and material-specific biomarkers which may allow early detection and intervention in a patient with adverse periprosthetic tissue reactions to metal wear debris.

Indexed as

Lymphocyte-dominatedMacrophage-dominatedMetal debrisMetal-on-MetalModularityPeriprosthetic tissue responseTaper corrosionTotal hip arthroplasty

Identifiers

PMID25405095
PMCPMC4133474

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.