Evidence map›Paper›PMID 25405025›Full record

ReviewAutoimmune diseases2014

Occurrence of Autoimmune Diseases Related to the Vaccine against Yellow Fever.

Ana Cristina Vanderley Oliveira, Licia Maria Henrique da Mota, Leopoldo Luiz Dos Santos-Neto, Jozélio Freire De Carvalho, Iramaya Rodrigues Caldas, Olindo Assis Martins Filho, Pedro Luis Tauil

Open access · goldAbstract readReview
In one paragraph

Review in Autoimmune diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Clinical Features of Human Infection by Yellow Fever.Methods in molecular biology (Clifton, N.J.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ana Cristina Vanderley OliveiraFaculdade de Medicina, Universidade de Brasília, Brasília, DF, Brazil ; CRDF, SHLN Bloco L Centro Cínico Norte II, 70910-900 Brasília, DF, Brazil.
Licia Maria Henrique da MotaFaculdade de Medicina, Universidade de Brasília, Brasília, DF, Brazil.
Leopoldo Luiz Dos Santos-NetoFaculdade de Medicina, Universidade de Brasília, Brasília, DF, Brazil.
Jozélio Freire De CarvalhoHospital Universitário Professor Edgard Santos da Universidade Federal da Bahia, 70390-700 Salvador, BA, Brazil.
Iramaya Rodrigues CaldasCoordenação de Pesquisa da Fundação Oswaldo Cruz (FIOCRUZ), 41810-080 Brasília, DF, Brazil.
Olindo Assis Martins FilhoLaboratório de Biomarcadores de Diagnóstico e Monitoração do Centro de Pesquisas René Rachou, FIOCRUZ, 21040-900 Belo Horizonte, MG, Brazil.
Pedro Luis TauilFaculdade de Medicina, Universidade de Brasília, Brasília, DF, Brazil.
Universidade de Brasília · BRFundação Oswaldo Cruz · BRUniversidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Yellow fever is an infectious disease, endemic in South America and Africa. This is a potentially serious illness, with lethality between 5 and 40% of cases. The most effective preventive vaccine is constituted by the attenuated virus strain 17D, developed in 1937. It is considered safe and effective, conferring protection in more than 90% in 10 years. Adverse effects are known as mild reactions (allergies, transaminases transient elevation, fever, headache) and severe (visceral and neurotropic disease related to vaccine). However, little is known about its potential to induce autoimmune responses. This systematic review aims to identify the occurrence of autoinflammatory diseases related to 17D vaccine administration. Six studies were identified describing 13 possible cases. The diseases were Guillain-Barré syndrome, multiple sclerosis, multiple points evanescent syndrome, acute disseminated encephalomyelitis, autoimmune hepatitis, and Kawasaki disease. The data suggest that 17D vaccination may play a role in the mechanism of loss of self-tolerance.

Identifiers

PMID25405025
PMCPMC4227414
OpenAlexW2141928565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.