ReviewInternational journal of chronic obstructive pulmonary disease2014
Oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease.
Review in International journal of chronic obstructive pulmonary disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Pooled it
- Oxygen therapy in the pre-hospital setting for acute exacerbations of chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2020Pooled it
- Adjuvant therapy efficacy of Chinese drugs pharmaceutics for COPD patients with respiratory failure: a meta-analysis.Bioscience reports · 2019Pooled it
- Prehospital continuous positive airway pressure for acute respiratory failure: the ACUTE feasibility RCT.Health technology assessment (Winchester, England) · 2021Trial
- Automated oxygen titration and weaning with FreeO2 in patients with acute exacerbation of COPD: a pilot randomized trial.International journal of chronic obstructive pulmonary disease · 2016Trial
- Trial
- Chronic Hypercapnic Respiratory Failure in COPD in Lithuania: National Registry Trends and Prehospital Emergency-Care Professionals' Knowledge of Hypercapnia and Oxygen Therapy.Diagnostics (Basel, Switzerland) · 2026Article
- Chronic lung diseases and kidney disease: pathophysiology and management.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Psychometric Properties of the Turkish Version of the Breathlessness Catastrophizing Scale in Patients with Chronic Obstructive Pulmonary Disease.Thoracic research and practice · 2025Article
- Efficacy of a hydrogen-oxygen generator in treating cigarette smoke-induced chronic obstructive pulmonary disease in rats.Current research in toxicology · 2025Article
- Practice of oxygen administration in patients hospitalized in internal medicine wards and intensive care units: A single-center prospective, observational study.Sao Paulo medical journal = Revista paulista de medicina · 2025Observational
- Review
- Navigating Pediatric Cor Pulmonale: A Comprehensive Review of Diagnosis and Management.Cureus · 2024Review
- Acute ischemic colitis complicating an exacerbation of chronic obstructive pulmonary disease: A case report of gut-lung crosstalk.SAGE open medical case reports · 2024Article
- Article
- Hypoxemia and not hyperoxemia predicts worse outcome in severe COPD exacerbations - an observational study.European clinical respiratory journal · 2023Article
- NEWS2, patient safety and hypercapnic respiratory failure.Clinical medicine (London, England) · 2022Review
- Hyperoxia combined with the B-cell antagonist rituximab led to intestinal dysbiosis in neonatal mice.Microbiology and immunology · 2022Article
- Evaluating Triple Therapy Treatment Pathways in Chronic Obstructive Pulmonary Disease (COPD): A Machine-Learning Predictive Model.International journal of chronic obstructive pulmonary disease · 2022Article
- Acute Beetroot Juice Ingestion Does Not Alter Renal Hemodynamics during Normoxia and Mild Hypercapnia in Healthy Young Adults.Nutrients · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute exacerbations of chronic obstructive pulmonary disease (COPD) are important events in the history of this debilitating lung condition. Associated health care utilization and morbidity are high, and many patients require supplemental oxygen or ventilatory support. The last 2 decades have seen a substantial increase in our understanding of the best way to manage the respiratory failure suffered by many patients during this high-risk period. This review article examines the evidence underlying supplemental oxygen therapy during exacerbations of COPD. We first discuss the epidemiology and pathophysiology of respiratory failure in COPD during exacerbations. The rationale and evidence underlying oxygen therapy, including the risks when administered inappropriately, are then discussed, along with further strategies for ventilatory support. We also review current recommendations for best practice, including methods for improving oxygen provision in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.