SynthesisEuropean archives of psychiatry and clinical neuroscience2015
The German guidelines for the treatment of anxiety disorders.
Synthesis in European archives of psychiatry and clinical neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Internet psychotherapeutic interventions for anxiety disorders - a critical evaluation.BMC psychiatry · 2022Pooled it
- Does cognitive behavioral therapy for anxiety disorders assist the discontinuation of benzodiazepines among patients with anxiety disorders? A systematic review and meta-analysis.Psychiatry and clinical neurosciences · 2021Pooled it
- Deprescribing benzodiazepine receptor agonists: Evidence-based clinical practice guideline.Canadian family physician Medecin de famille canadien · 2018Guideline
- Effectiveness of noninvasive brain stimulation in the treatment of anxiety disorders: a meta-analysis of sham or behaviour-controlled studies.Journal of psychiatry & neuroscience : JPNPooled it
- Epidemiology, genetics, neuroimaging, clinical features, and treatment between overall and performance-only social anxiety disorder: a narrative review.Dialogues in clinical neuroscience · 2026Review
- Clinical features and genetic mechanisms of anxiety, fear, and avoidance: A comprehensive review of five anxiety disorders.Molecular psychiatry · 2025Review
- Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex.Translational psychiatry · 2024Article
- Association between benzodiazepine anxiolytic polypharmacy and concomitant psychotropic medications in Japan: a retrospective cross-sectional study.Frontiers in psychiatry · 2024Article
- Clinical practice for unspecified anxiety disorder in primary care.PCN reports : psychiatry and clinical neurosciences · 2023Article
- Management of unspecified anxiety disorder: Expert consensus.Neuropsychopharmacology reports · 2023Article
- Preliminary Evaluation of Translated and Culturally Adapted Internet-Delivered Cognitive Therapy for Social Anxiety Disorder: Multicenter, Single-Arm Trial in Japan.JMIR formative research · 2023Article
- Individual cognitive therapy reduces frontal-thalamic resting-state functional connectivity in social anxiety disorder.Frontiers in psychiatry · 2023Article
- Development and acceptability of a decision aid for anxiety disorder considering discontinuation of benzodiazepine anxiolytic.Frontiers in psychiatry · 2023Article
- Differential effects of the translocator protein 18 kDa (TSPO) ligand etifoxine and the benzodiazepine alprazolam on startle response to predictable threat in a NPU-threat task after acute and short-term treatment.Psychopharmacology · 2022Article
- The German Guidelines for the treatment of anxiety disorders: first revision.European archives of psychiatry and clinical neuroscience · 2022Article
- Comparative safety of chronic versus intermittent benzodiazepine prescribing in older adults: A population-based cohort study.Journal of psychopharmacology (Oxford, England) · 2022Article
- Efficacy of Acupuncture for Parkinson's Disease Anxiety: Two-Stage Protocol for a Randomized Controlled Clinical Trial.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Incidence of and Characteristics Associated With Long-term Benzodiazepine Use in Finland.JAMA network open · 2020Article
- The Association between Physical Activity and Anxiety Symptoms for General Adult Populations: An Analysis of the Dose-Response Relationship.Psychiatry investigation · 2020Article
- Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A consensus group consisting of 36 experts representing 20 leading German specialist societies and patient self-help organizations developed evidence-based recommendations for the treatment of anxiety disorders in Germany. These were based on a systematic review of randomized controlled trials on anxiety disorders (n = 403) and on preexisting German and international guidelines. According to the consensus committee, anxiety disorders should be treated with psychotherapy or pharmacological drugs or a combination of both. Cognitive behavioral therapy (CBT) was regarded as the psychological treatment with the highest level of evidence. Psychodynamic therapy (PDT) was recommended for cases in which CBT was not effective or not available or in which PDT was the informed patient's preferred option. First-line drugs for anxiety disorders include selective serotonin reuptake inhibitors and serotonin-noradrenaline reuptake inhibitors. After remission, medications should be continued for 6-12 months. When either drug or psychotherapy was not effective, treatment should be switched to the other approach or to a combination of both. For patients non-responsive to standard treatments, alternative strategies are suggested. When developing a treatment plan, efficacy, side effects, costs and the preference of the patient should be considered. A large amount of data available from randomized controlled trials permit the formulation of robust evidence-based recommendations for the treatment of anxiety disorders. The recommendations were not only developed for the special situation in Germany, but may also be helpful for developing treatment plans in other countries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.