ArticleThe American journal of tropical medicine and hygiene2015
Epidemiology and individual, household and geographical risk factors of podoconiosis in Ethiopia: results from the first nationwide mapping.
Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.
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Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Mapping the global distribution of podoconiosis: Applying an evidence consensus approach.PLoS neglected tropical diseases · 2019Pooled it
- Global epidemiology of podoconiosis: A systematic review.PLoS neglected tropical diseases · 2018Pooled it
- Association between footwear use and neglected tropical diseases: a systematic review and meta-analysis.PLoS neglected tropical diseases · 2014Pooled it
- Lymphoedema management to prevent acute dermatolymphangioadenitis in podoconiosis in northern Ethiopia (GoLBeT): a pragmatic randomised controlled trial.The Lancet. Global health · 2018Trial
- Podoconiosis treatment in northern Ethiopia (GoLBet): study protocol for a randomised controlled trial.Trials · 2015Trial
- Determinants of podoconiosis at the age of 15 years and above at Dera Woreda, South Gondar zone, Northwest Ethiopia.BMC public health · 2025Article
- Healthcare professionals' knowledge, attitudes, and practice of podoconiosis management and associated factors in public hospitals in Ilu Ababor and Buno Bedelle zones, Southwest Ethiopia: a cross-sectional study.Frontiers in public health · 2025Article
- Podoconiosis in Uganda: prevalence, geographical distribution and risk factors.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2024Article
- Hematological and immunological profiles of podoconiosis patients in West Gojjam Zone, Ethiopia: A comparative cross-sectional study.PLoS neglected tropical diseases · 2024Article
- Differences in Cytokine Expression at Baseline and in Response to Mineral Stimulation by Peripheral Blood Mononuclear Cells from Podoconiosis Cases and Healthy Control Individuals.Tropical medicine and infectious disease · 2024Article
- Sero-antigen prevalence of lymphatic filariasis and risk factors of podoconiosis in Busiriba sub-county, Kamwenge district, Southwestern Uganda, August-September 2018.BMC research notes · 2024Article
- The role of a community conversation intervention in reducing stigma related to lower limb lymphoedema in Northern Ethiopia.BMC health services research · 2024Article
- Tropical leg lymphedema caused by podoconiosis is associated with increased colonisation by anaerobic bacteria.Scientific reports · 2023Article
- Determinants of Podoconiosis in Bensa District, Sidama Region, Ethiopia: A case control study.PLoS neglected tropical diseases · 2023Article
- Phenotypical characterization, and antibiotics susceptibility patterns of skin bacteria found in podoconiosis patients in the North West Region of Cameroon.BMC microbiology · 2023Article
- From Neglected to Public Health Burden: Factors Associated with Podoconiosis in Resource Limited Setting in Case of Southwest Ethiopia: A Community Based Cross Sectional Study.Research and reports in tropical medicine · 2023Article
- Epidemiology of podoconiosis in sub-Saharan Africa: A systematic review and meta-analysis.SAGE open medicine · 2023Review
- An analysis of social dimensions of podoconiosis and leprosy on affected households in endemic health districts of the North West Region of Cameroon.SSM - population health · 2022Article
- Quantifying Population Burden and Effectiveness of Decentralized Surveillance Strategies for Skin-Presenting Neglected Tropical Diseases, Liberia.Emerging infectious diseases · 2022Article
- A qualitative process evaluation of a community conversation intervention to reduce stigma related to lower limb lymphoedema in Northern Ethiopia.BMC health services research · 2022Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
Although podoconiosis is one of the major causes of tropical lymphoedema and is endemic in Ethiopia its epidemiology and risk factors are poorly understood. Individual-level data for 129,959 individuals from 1,315 communities in 659 woreda (districts) were collected for a nationwide integrated survey of lymphatic filariasis and podoconiosis. Blood samples were tested for circulating Wuchereria bancrofti antigen using immunochromatographic card tests. A clinical algorithm was used to reach a diagnosis of podoconiosis by excluding other potential causes of lymphoedema of the lower limb. Bayesian multilevel models were used to identify individual and environmental risk factors. Overall, 8,110 of 129,959 (6.2%, 95% confidence interval [CI] 6.1-6.4%) surveyed individuals were identified with lymphoedema of the lower limb, of whom 5,253 (4.0%, 95% CI 3.9-4.1%) were confirmed to be podoconiosis cases. In multivariable analysis, being female, older, unmarried, washing the feet less frequently than daily, and being semiskilled or unemployed were significantly associated with increased risk of podoconiosis. Attending formal education and living in a house with a covered floor were associated with decreased risk of podoconiosis. Podoconiosis exhibits marked geographical variation across Ethiopia, with variation in risk associated with variation in rainfall, enhanced vegetation index, and altitude.
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