ArticleThe American journal of tropical medicine and hygiene2015
Bed bugs (Cimex lectularius) as vectors of Trypanosoma cruzi.
Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
68 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Prevalence ofFrontiers in veterinary science · 2021Pooled it
- Bed bugs and possible transmission of human pathogens: a systematic review.Archives of dermatological research · 2016Pooled it
- Chagas Disease in the 21st Century: Global Spread, Ecological Shifts, and Research Frontiers.Biology · 2025Review
- Fate of Trypanosoma cruzi, the causative agent of Chagas disease, in bed bugs after oral ingestion or intrathoracic injection.PLoS neglected tropical diseases · 2025Article
- The patent landscape of Chagas disease vaccines indicates major underinvestment in an emerging global health threat.Nature biotechnology · 2025Article
- Trypanosoma dionisii in China: ecology and tentative epidemiology.Infectious diseases of poverty · 2025Article
- Beyond Mosquitoes: A Review of Pediatric Vector-Borne Diseases Excluding Malaria and Arboviral Infections.Pathogens (Basel, Switzerland) · 2025Review
- Article
- Common Bed Bugs: Non-Viable Hosts forCells · 2024Article
- Article
- Phylogeny and evolution of hemipteran insects based on expanded genomic and transcriptomic data.BMC biology · 2024Article
- A novel prolixicin identified in common bed bugs with activity against both bacteria and parasites.Scientific reports · 2024Article
- The Hidden Hand of Asymptomatic Infection Hinders Control of Neglected Tropical Diseases: A Modeling Analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Interaction ofMicroorganisms · 2024Review
- Irrigation, migration and infestation: a case study of Chagas disease vectors and bed bugs in El Pedregal, Peru.Memorias do Instituto Oswaldo Cruz · 2024Article
- Perceptions of Problems with Household Insects: Qualitative and Quantitative Findings from Peri-Urban Communities in Arequipa, Peru.The American journal of tropical medicine and hygiene · 2023Article
- Bed Bugs (Hemiptera, Cimicidae): A Global Challenge for Public Health and Control Management.Diagnostics (Basel, Switzerland) · 2023Review
- Cimicids of Medical and Veterinary Importance.Insects · 2023Review
- Histamine Excretion by the Common Bed Bug (Hemiptera: Cimicidae).Journal of medical entomology · 2022Article
- Polyctenidae (Hemiptera: Cimicoidea) species in the Afrotropical region: Distribution, host specificity, and first insights to their molecular phylogeny.Ecology and evolution · 2022Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Populations of the common bed bug, Cimex lectularius, have recently undergone explosive growth. Bed bugs share many important traits with triatomine insects, but it remains unclear whether these similarities include the ability to transmit Trypanosoma cruzi, the etiologic agent of Chagas disease. Here, we show efficient and bidirectional transmission of T. cruzi between hosts and bed bugs in a laboratory environment. Most bed bugs that fed on experimentally infected mice acquired the parasite. A majority of previously uninfected mice became infected after a period of cohabitation with exposed bed bugs. T. cruzi was also transmitted to mice after the feces of infected bed bugs were applied directly to broken host skin. Quantitative bed bug defecation measures were similar to those of important triatomine vectors. Our findings suggest that the common bed bug may be a competent vector of T. cruzi and could pose a risk for vector-borne transmission of Chagas disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.