ArticleWorld journal of surgery2015
Surgical treatment of incidental gallbladder cancer discovered during or following laparoscopic cholecystectomy.
Article in World journal of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Safe, selective histopathological examination of gallbladder specimens: a systematic review.The British journal of surgery · 2020Pooled it
- Low-grade appendiceal mucinous neoplasms combined with incidental gallbladder cancer: a case report.AME case reports · 2026Article
- Incidental Gallbladder Cancer: A Comprehensive Review.Journal of gastrointestinal cancer · 2025Review
- Laparoscopic Conversion to Open Cholecystectomy: Is Incidental Gallbladder Cancer Any Different?Cureus · 2024Article
- Decoding the Conundrum: Navigating Intra-operatively Encountered Suspicious Gallbladder Wall Thickening with Laparoscopic Transhepatic Needle Decompression and Beyond Cystic Plate Cholecystectomy.Annals of surgical oncology · 2024Article
- Risk stratification of gallbladder masses by machine learning-based ultrasound radiomics models: a prospective and multi-institutional study.European radiology · 2023Article
- LaparoscopicWorld journal of clinical cases · 2023Article
- ASO Author Reflections: Robotic Radical Surgery for Incidental Gallbladder Cancer is on the Rise.Annals of surgical oncology · 2023Article
- Robotic Hepatic Bisegmentectomy (s4b + s5) and Hilar Lymphadenectomy for Incidental Gallbladder Cancer Using Glissonian Approach.Annals of surgical oncology · 2023Article
- Reappraisal of T1b gallbladder cancer (GBC): clinicopathologic analysis of 473 in situ and invasive GBCs and critical review of the literature highlights its rarity, and that it has a very good prognosis.Virchows Archiv : an international journal of pathology · 2023Review
- Incidental gallbladder cancer: what is the prevalence and how do we perform cholecystectomy for presumably benign biliary disease?Revista do Colegio Brasileiro de Cirurgioes · 2023Observational
- Unusual Case of Gallbladder Adenocarcinoma Metastasis to the Abdominal Wall 11 Years Later: Synchronous Presentation with Two Malignant Colon Tumors, Coincidence or Not?Case reports in surgery · 2021Article
- Long-term outcomes of incidental gallbladder carcinoma without additional resection: A single institution experiment.Molecular and clinical oncology · 2020Article
- Incidental gallbladder cancer after laparoscopic cholecystectomy: incidence, management, and prognosis.Asia-Pacific journal of clinical oncology · 2020Article
- Incidental Carcinoma after Cholecystectomy for Benign Disease of the Gallbladder: A Meta-Analysis.Journal of clinical medicine · 2020Article
- Is combined extra-hepatic bile-duct resection justified for advanced gallbladder carcinoma?Gastroenterology report · 2019Article
- Bile spillage and incidental gall bladder adenocarcinoma.Hepatobiliary surgery and nutrition · 2019Article
- Article
- Prospective multi-center study of surgeon's assessment of the gallbladder compared to histopathological examination to detect incidental malignancy.Langenbeck's archives of surgery · 2019Article
- Gallbladder cancer in Eastern Province of Saudi Arabia: A retrospective cohort study.Annals of medicine and surgery (2012) · 2018Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optimal surgical management of patients with incidental gallbladder cancer (IGBC) and their long-term survival remains unclear.
objectiveThe purpose of this study was to examine the long-term prognosis of patients with IGBC diagnosed during or after LC.
methodsBetween January 2002 and January 2012, a total of 7,582 consecutive patients underwent LC for presumed gallbladder benign disease in the Chinese PLA General Hospital, China. Among them, 69 patients (0.91%) were diagnosed to have IGBC. Their medical records, imaging data, surgery records, pathological findings, and survival data were retrospectively reviewed.
resultsMedian age was 61 years (range: 34-83). After a median follow-up period of 61 months, the 1-, 3-, and 5-year survival rates of patients were 89.9, 78.3, and 76.8%, respectively. The 5-year survival rates of patients with T1a, T1b, T2, and T3 stages were 95.5, 93.8, 69.2, and 44.4%, respectively. The 5-year survival rates in simple LC (n = 45), converted to open extended cholecystectomy (n = 16), and radical second resection (n = 8) groups were 91.1, 37.5, and 75.0%, respectively. Local port-site tumor recurrence was identified in one patient. Prognostic factors including depth of invasion, lymph node status, vascular or neural invasion, tumor differentiation, extent of resection, bile spillage, and type of surgery were statistically significant (p < 0.05).
conclusionsSimple LC is appropriate for T1a patients with clear margin and unbroken gallbladder, whereas extended radical resection is recommended for patients with T1b or more advanced IGBC. An intact surgical specimen and the use of plastic retrieval bags are important to reduce the risk of port-site recurrences and disease relapse. Early diagnosis, meticulous perioperative assessment, and precise surgery are essential factors to obtain good results in IGBC treatment.
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