Trial reportBMC neurology2014
Improved nutritional status is related to improved quality of life in Parkinson's disease.
Trial report in BMC neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- How quality of life is measured in studies of nutritional intervention: a systematic review.Health and quality of life outcomes · 2024Pooled it
- Implication of nutrition in severity of symptoms and treatments in quality of life in Parkinson's disease: a systematic review.Frontiers in nutrition · 2024Pooled it
- Prevalence of Malnutrition in Patients with Parkinson's Disease: A Systematic Review.Nutrients · 2022Pooled it
- When the Scale Drops: Pathways to Weight Loss in Parkinson's Disease and Future Directions.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- When the Scale Drops: Pathways to Weight Loss in Parkinson's Disease and Future Directions.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- A narrative review of clinical and non-clinical determinants of health-related quality of life in advanced Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Dietary habits and adherence to the Mediterranean diet in a cohort of Parkinson's disease patients in Lithuania.Frontiers in nutrition · 2026Article
- Vital nutrition: enhancing health in advanced Parkinson's disease with device-aided therapies.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Nutritional and dietary clinical trials for Parkinson's disease: a narrative review.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Impact of the Ketogenic Diet on Neurological Diseases: A Review.Life (Basel, Switzerland) · 2025Review
- A 15-year bibliometric analysis of body mass index moderation in the management of Parkinson's disease.Frontiers in aging neuroscience · 2025Article
- Polish translation, cultural adaptation, and validity confirmation of the Scored Patient-Generated Subjective Global Assessment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- The Gut Microbiota in Parkinson Disease: Interactions with Drugs and Potential for Therapeutic Applications.CNS drugs · 2024Article
- The Role of Diet in Parkinson's Disease.Journal of Parkinson's disease · 2024Review
- To restrict or not to restrict? Practical considerations for optimizing dietary protein interactions on levodopa absorption in Parkinson's disease.NPJ Parkinson's disease · 2023Review
- Diet quality, sleep and quality of life in Parkinson's disease: a cross-sectional study.Irish journal of medical science · 2023Article
- Mobile health technology, exercise adherence and optimal nutrition post rehabilitation among people with Parkinson's Disease (mHEXANUT) - a randomized controlled trial protocol.BMC neurology · 2023Article
- Temporal Muscle Thickness Correlates with Sarcopenia in Parkinson's Disease.Journal of Parkinson's disease · 2023Article
- Nutrition Education Programs for Adults with Neurological Diseases Are Lacking: A Scoping Review.Nutrients · 2022Article
- Factors Contributing to Malnutrition in Parkinson's Disease Patients With Freezing of Gait.Frontiers in neurology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuality of life is poorer in Parkinson's disease than in other conditions and in the general population without Parkinson's disease. Malnutrition also results in poorer quality of life. This study aimed at determining the relationship between quality of life and nutritional status.
methodsCommunity-dwelling people with Parkinson's disease >18 years old were recruited. The Patient-Generated Subjective Global Assessment (PG-SGA) assessed nutritional status. The Parkinson's Disease Questionnaire 39 (PDQ-39) measured quality of life. Phase I was cross-sectional. The malnourished in Phase I were eligible for a nutrition intervention phase, randomised into 2 groups: standard care (SC) with provision of nutrition education materials only and intervention (INT) with individualised dietetic advice and regular weekly follow-up. Data were collected at baseline, 6 weeks, and 12 weeks.
resultsPhase I consisted of 120 people who completed the PDQ-39. Phase II consisted of 9 in the SC group and 10 in the INT group. In Phase I, quality of life was poorer in the malnourished, particularly for mobility and activities of daily living domains. There was a significant correlation between PG-SGA and PDQ-39 scores (Phase I, rs = 0.445, p = .000; Phase II, rs = .426, p = .002). In Phase II, no significant difference in the PDQ-39 total or sub-scores was observed between the INT and SC groups; however, there was significant improvement in the emotional well-being domain for the entire group, X2(2) = 8.84, p = .012.
conclusionsMalnourished people with Parkinson's disease had poorer quality of life than the well-nourished, and improvements in nutritional status resulted in quality of life improvements. Attention to nutritional status is an important component of quality of life and therefore the total care of people with Parkinson's disease.
trial registrationACTRN12610000819022.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.