ArticleMolecular ecology2015
The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus.
Article in Molecular ecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 91 citations in OpenAlex.
- Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower.The New phytologist · 2026Article
- Maintenance of phenotypic divergence in two sympatric monkeyflowers with weak reproductive isolation.bioRxiv : the preprint server for biology · 2026Article
- Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower.bioRxiv : the preprint server for biology · 2025Article
- Intraspecific variation in seed dispersal between annual and perennial populations.Annals of botany · 2025Article
- Unique genetic bases of repeated life-history divergence associated with high altitude adaptation inbioRxiv : the preprint server for biology · 2025Article
- The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024Review
- Origin of biogeographically distinct ecotypes during laboratory evolution.Nature communications · 2024Article
- Twilight length alters growth and flowering time in Arabidopsis viaScience advances · 2024Article
- Demographic consequences of an extreme heat wave are mitigated by spatial heterogeneity in an annual monkeyflower.Ecology and evolution · 2023Article
- Facultative Annual Life Cycles in Seagrasses.Plants (Basel, Switzerland) · 2023Review
- Taking quantitative genomics into the wild.Proceedings. Biological sciences · 2022Article
- Climate and the biotic community structure plant resistance across biogeographic groups of yellow monkeyflower.Ecology and evolution · 2022Article
- Chromosomal Fusions Facilitate Adaptation to Divergent Environments in Threespine Stickleback.Molecular biology and evolution · 2022Article
- Convergent evolution of the annual life history syndrome from perennial ancestors.Frontiers in plant science · 2022Review
- The role of genus and life span in predicting seed and vegetative trait variation and correlation in Lathyrus, Phaseolus, and Vicia.American journal of botany · 2021Article
- The genetic architecture and evolution of life-history divergence among perennials in theProceedings. Biological sciences · 2021Article
- Population genomic and historical analysis suggests a global invasion by bridgehead processes in Mimulus guttatus.Communications biology · 2021Article
- Multi-level patterns of genetic structure and isolation by distance in the widespread plant Mimulus guttatus.Heredity · 2020Article
- Adaptation via pleiotropy and linkage: Association mapping reveals a complex genetic architecture within the sticklebackEvolution letters · 2020Article
- Patterns of Hybrid Seed Inviability in the Mimulus guttatus sp. Complex Reveal a Potential Role of Parental Conflict in Reproductive Isolation.Current biology : CB · 2020Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differential natural selection acting on populations in contrasting environments often results in adaptive divergence in multivariate phenotypes. Multivariate trait divergence across populations could be caused by selection on pleiotropic alleles or through many independent loci with trait-specific effects. Here, we assess patterns of association between a suite of traits contributing to life history divergence in the common monkey flower, Mimulus guttatus, and examine the genetic architecture underlying these correlations. A common garden survey of 74 populations representing annual and perennial strategies from across the native range revealed strong correlations between vegetative and reproductive traits. To determine whether these multitrait patterns arise from pleiotropic or independent loci, we mapped QTLs using an approach combining high-throughput sequencing with bulk segregant analysis on a cross between populations with divergent life histories. We find extensive pleiotropy for QTLs related to flowering time and stolon production, a key feature of the perennial strategy. Candidate genes related to axillary meristem development colocalize with the QTLs in a manner consistent with either pleiotropic or independent QTL effects. Further, these results are analogous to previous work showing pleiotropy-mediated genetic correlations within a single population of M. guttatus experiencing heterogeneous selection. Our findings of strong multivariate trait associations and pleiotropic QTLs suggest that patterns of genetic variation may determine the trajectory of adaptive divergence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.