Trial reportHemodialysis international. International Symposium on Home Hemodialysis2015
Longitudinal associations of depressive symptoms and pain with quality of life in patients receiving chronic hemodialysis.
Trial report in Hemodialysis international. International Symposium on Home Hemodialysis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00692419 (Pain, Sexual Dysfunction and Depression in Hemodialysis Patients), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pain, Sexual Dysfunction and Depression in Hemodialysis Patients
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Interventions for improving health literacy in people with chronic kidney disease.The Cochrane database of systematic reviews · 2022Pooled it
- Psychosocial interventions for preventing and treating depression in dialysis patients.The Cochrane database of systematic reviews · 2019Pooled it
- eHealth interventions for people with chronic kidney disease.The Cochrane database of systematic reviews · 2019Pooled it
- Trial
- The Relationship Between Religious Coping and Quality of Life of Hemodialysis Patients in Somalia.Journal of religion and health · 2026Article
- The impact of chronic kidney disease on patient and caregiver quality of life: A qualitative study in Spain.PloS one · 2026Observational
- The Significance of Palliative Care in Managing Pain for Patients Undergoing Hemodialysis.Journal of clinical medicine · 2025Article
- Review
- Music-based interventions for people with chronic kidney disease undergoing haemodialysis.The Cochrane database of systematic reviews · 2025Article
- Prevalence of Knee Pain and Its Relation to Depression, Anxiety, and Health-Related Quality of Life Among Maintenance Hemodialysis Patients.Journal of clinical medicine · 2025Article
- Symptom profiles in patients receiving maintenance hemodialysis and their association with quality of life: a longitudinal study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Screening for depression in chronic haemodialysis patients as a part of care in dialysis setting: a cross-sectional study.Frontiers in psychiatry · 2024Article
- Taking care of myself in a different and broken world: self-care practices of adolescents on dialysis.International journal of qualitative studies on health and well-being · 2023Article
- The incidence of pain and its association with quality of life in patients with peritoneal dialysis.Renal failure · 2022Article
- The Higher the CKD Stage, the Higher the Psychological Stress in Patients with CKD during COVID-19 Pandemic.Journal of clinical medicine · 2022Article
- Self-care self-efficacy and depression associated with quality of life among patients undergoing hemodialysis in Vietnam.PloS one · 2022Article
- Physical performance and health-related quality of life among older adults on peritoneal dialysis: a cross-sectional study.International urology and nephrology · 2021Article
- Quality of life of chronic kidney patients on hemodialysis and related factors.Revista latino-americana de enfermagem · 2020Article
- Treating symptoms to improve the quality of life in patients on chronic hemodialysis.International urology and nephrology · 2019Article
- The prevalence of depression and the association between depression and kidney function and health-related quality of life in elderly patients with chronic kidney disease: a multicenter cross-sectional study.Clinical interventions in aging · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Depressive symptoms and pain are common in patients on chronic hemodialysis (HD), yet their associations with quality of life (QOL) are not fully understood. We sought to characterize the longitudinal associations of these symptoms with QOL. As part of a trial comparing two symptom management strategies in patients receiving chronic HD, we assessed depressive symptoms using the Patient Health Questionnaire-9 (PHQ-9), and pain using the Short Form McGill Pain Questionnaire (SF-MPQ) monthly over 24 months. We assessed health-related QOL (HR-QOL) quarterly using the Short Form 12 (SF-12) and global QOL (G-QOL) using a single-item survey. We used random effects linear regression to analyze the independent associations of depressive symptoms and pain, scaled based on 5-point increments in symptom scores, with HR-QOL and G-QOL. Overall, 286 patients completed 1417 PHQ-9 and SF-MPQ symptom assessments, 1361 SF-12 assessments, and 1416 G-QOL assessments. Depressive symptoms were independently and inversely associated with SF-12 physical HR-QOL scores (β = -1.09; 95% confidence interval [CI]: -1.69, -0.50, P < 0.001); SF-12 mental HR-QOL scores (β = -4.52; 95% CI: -5.15, -3.89, P < 0.001); and G-QOL scores (β = -0.64; 95%CI: -0.79, -0.49, P < 0.001). Pain was independently and inversely associated with SF-12 physical HR-QOL scores (β = -0.99; 95% CI: -1.30, -0.68, P < 0.001) and G-QOL scores (β = -0.12; 95%CI: -0.20, -0.05, P = 0.002); but not with SF-12 mental HR-QOL scores (β = -0.16; 95%CI: -0.050, 0.17, P = 0.34). In patients receiving chronic HD, depressive symptoms and to a lesser extent pain, are independently associated with reduced HR-QOL and G-QOL. Interventions to alleviate these symptoms could potentially improve patients' HR-QOL and G-QOL.
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