Evidence map›Paper›PMID 25402608›Full record

ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre2015

Serum myeloperoxidase level is associated with heart-type fatty acid-binding protein but not troponin T in patients with chronic heart failure.

Omer Gedikli, Abdulkadir Kiris, Yusuf Hosoglu, Caner Karahan, Sahin Kaplan

Open access · diamondAbstract read
In one paragraph

Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. NADCell communication and signaling : CCS · 2024
    Review
  2. New Insight in Cardiorenal Syndrome: From Biomarkers to Therapy.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Article
  5. Biomarkers in Cardiorenal Syndromes.BioMed research international · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Omer GedikliDepartment of Cardiology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Abdulkadir Kiris
Yusuf Hosoglu
Caner Karahan
Sahin Kaplan
Karadeniz Technical University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOur aim was to investigate the possible relationship between myeloperoxidase (MPO) and myocardial damage markers such as heart-type fatty acid-binding protein (H-FABP) and troponin T (TnT) in patients with chronic heart failure (HF). MATERIALS AND

methodsForty-two consecutive patients (age range: 27-80 years) with chronic HF were enrolled in the study. Serum H-FABP, TnT and MPO levels were measured. Routine biochemical and clinical parameters were recorded. Echocardiographic examinations were performed on all patients. A linear regression analysis was performed to determine the correlates of serum H-FABP.

resultsThe MPO, H-FABP and TnT levels were 255 ± 227, 60.6 ± 48.5 and 0.07 ± 0.15 ng/ml, respectively. In multiple linear regression analysis, age (β = -0.36, p = 0.006), creatinine level (β = 0.3, p = 0.024) and serum MPO level (β = 0.41, p = 0.009) were significant determinants of H-FABP levels. Bivariate predictors were not significantly associated with TnT levels in linear regression analyses.

conclusionsThe MPO was significantly associated with serum H-FABP levels but not with TnT.

Indexed as

AdultAgedAged, 80 and overBiomarkersBlood Urea NitrogenChronic DiseaseEchocardiographyFatty Acid-Binding ProteinsFemaleHeart FailureHumansLinear ModelsMaleMiddle AgedOutpatientsPeroxidaseBiomarkersFatty Acid-Binding ProteinsPeroxidaseTroponin T

Identifiers

PMID25402608
PMCPMC5588196
OpenAlexW2001564641

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.