Evidence map›Paper›PMID 25402474›Full record

ArticlePloS one2014

The 5-year onset and regression of diabetic retinopathy in Chinese type 2 diabetes patients.

Peiyao Jin, Jinjuan Peng, Haidong Zou, Weiwei Wang, Jiong Fu, Binjie Shen, Xuelin Bai, Xun Xu, Xi Zhang

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.

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  14. Declined incidence of patients treated for vision-threatening diabetic retinopathy in South Korea: a 12-year nationwide population-based study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Peiyao JinDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China.
Jinjuan PengDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China.
Haidong ZouDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China; Department of Preventative Ophthalmology, Shanghai Eye Disease Prevention and Treatment Center, Shanghai, 200040, China.
Weiwei WangBeixinjing Community Health Service Center, Shanghai, China.
Jiong FuBeixinjing Community Health Service Center, Shanghai, China.
Binjie ShenBeixinjing Community Health Service Center, Shanghai, China.
Xuelin BaiBeixinjing Community Health Service Center, Shanghai, China.
Xun XuDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China.
Xi ZhangDepartment of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, 20080, China.
Shanghai First People's Hospital · CNShanghai Medical Information Center · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the rate and risk factors of diabetic retinopathy (DR) onset and regression in Chinese type 2 diabetes mellitus patients.

methodsThis is a 5-year community-based prospective study. The demographic information, systemic examination results and ophthalmological test results of each participant were collected. The study outcomes were DR incidence, defined as the onset of DR in at least one eye, and DR regression, defined as full regression from existing DR to no retinopathy without invasive treatments. The associations between each potential risk factor and the outcomes were studied.

resultsIn total, 778 participants were enrolled. There were 322 patients without DR at baseline, of which 151 participants developed DR during follow-up (DR incidence rate = 46.89%). Baseline hyperglycemia and high blood pressure were two independent risk factors associated with DR incidence. Among the 456 participants with existing DR at entry, 110 fully recovered after 5 years (DR regression rate = 24.12%). Low baseline glucose and low serum triglyceride were two independent factors associated with DR regression.

conclusionsDR incidence occurred more frequently in patients with hyperglycemia and high blood pressure. DR regression occurred mostly in patients with lower glucose and lower serum triglyceride levels among Chinese type 2 diabetes patients.

Indexed as

AgedAged, 80 and overAge of OnsetChinaDiabetes Mellitus, Type 2Diabetic RetinopathyFemaleFollow-Up StudiesGlycated HemoglobinHumansHyperglycemiaHypertensionIncidenceInsulinMaleMiddle AgedGlycated HemoglobinInsulin

Identifiers

PMID25402474
PMCPMC4234658
OpenAlexW2088025031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.