ArticlePloS one2014
Regional differences of undiagnosed type 2 diabetes and prediabetes prevalence are not explained by known risk factors.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sex-specific differences in the prevalence of intermediate hyperglycaemia states: A systematic review and meta-analysis.Diabetic medicine : a journal of the British Diabetic Association · 2026Pooled it
- Incidence of lower extremity amputations in the diabetic compared with the non-diabetic population: A systematic review.PloS one · 2017Pooled it
- Predicting Factors for Metabolic Non-Response to a Complex Lifestyle Intervention-A Replication Analysis to a Randomized-Controlled Trial.Nutrients · 2022Trial
- Trial
- Cardiovascular profiling in the diabetic continuum: results from the population-based Gutenberg Health Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Observational
- Association of hepatic steatosis derived from ultrasound and quantitative MRI with prediabetes in the general population.Scientific reports · 2021Article
- Impact of diagnostic accuracy on the estimation of excess mortality from incidence and prevalence: simulation study and application to diabetes in German men.F1000Research · 2021Article
- Educational Level, but Not Income or Area Deprivation, is Related to Macrovascular Disease: Results From Two Population-Based Cohorts in Germany.International journal of public health · 2021Article
- Glucose and insulin levels are associated with arterial stiffness and concentric remodeling of the heart.Cardiovascular diabetology · 2019Article
- Social inequality and diabetes mellitus - developments over time among the adult population in Germany.Journal of health monitoring · 2019Article
- TeDia - A Telemedicine-Based Treatment Model for Inpatient and Interprofessional Diabetes Care.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Regional differences of macrovascular disease in Northeast and South Germany: the population-based SHIP-TREND and KORA-F4 studies.BMC public health · 2018Article
- Prevalence of moderately increased albuminuria among individuals with normal HbA1c level but impaired glucose tolerance: Results from the LIFE-Adult-Study.Endocrinology, diabetes & metabolism · 2018Article
- Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia.Nutrients · 2017 · on this mapReview
- Prevalence, incidence and mortality of diabetes mellitus in adults in Germany - A review in the framework of the Diabetes Surveillance.Journal of health monitoring · 2017Article
- 12-Month prevalence of known diabetes mellitus in Germany.Journal of health monitoring · 2017Article
- Rising prevalence of back pain in Austria: considering regional disparities.Wiener klinische Wochenschrift · 2016Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe have previously found regional differences in the prevalence of known type 2 diabetes between northeastern and southern Germany. We aim to also provide prevalence estimates for prediabetes (isolated impaired fasting glucose (i-IFG), isolated glucose intolerance (i-IGT), combined IFG and IGT) and unknown type 2 diabetes for both regions.
methodsPrevalence (95%CI) of prediabetes (i-IFG: fasting glucose 5.6-6.9 mmol/l; i-IGT: 2 h postchallenge glucose 7.8-11.0 mmol/l, oral glucose tolerance test (OGTT), ≥ 8 h overnight fasting) and unknown diabetes were analyzed in two regional population-based surveys (age group 35-79 years): SHIP-TREND (Study of Health in Pomerania (northeast), 2008-2012) and KORA F4 (Cooperative Health Research in the region of Augsburg (south), 2006-2008). Both studies used similar methods, questionnaires, and identical protocols for OGTT. Overall, 1,980 participants from SHIP-TREND and 2,617 participants from KORA F4 were included.
resultsAge-sex-standardized prevalence estimates (95%CI) of prediabetes and unknown diabetes were considerably higher in the northeast (SHIP-TREND: 43.1%; 40.9-45.3% and 7.1%; 5.9-8.2%) than in the south of Germany (KORA F4: 30.1%; 28.4-31.7% and 3.9%; 3.2-4.6%), respectively. In particular, i-IFG (26.4%; 24.5-28.3% vs. 17.2%; 15.7-18.6%) and IFG+IGT (11.2%; 9.8-12.6% vs. 6.6%; 5.7-7.5%) were more frequent in SHIP-TREND than in KORA. In comparison to normal glucose tolerance, the odds of having unknown diabetes (OR, 95%CI: 2.59; 1.84-3.65) or prediabetes (1.98; 1.70-2.31) was higher in the northeast than in the south after adjustment for known risk factors (obesity, lifestyle).
conclusionsThe regional differences of prediabetes and unknown diabetes are in line with the geographical pattern of known diabetes in Germany. The higher prevalences in the northeast were not explained by traditional risk factors.
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