Evidence map›Paper›PMID 25402180›Full record

ArticleComparative medicine2014

Micromelic dysplasia-like syndrome in a captive colony of common marmosets (Callithrix jacchus).

Leslie Bosseler, Pieter Cornillie, Jimmy H Saunders, Jaco Bakker, Jan A M Langermans, Christophe Casteleyn, Annemie Decostere, Koen Chiers

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Comparative medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Leslie BosselerDepartment of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium. leslie.bosseler@ugent.be.
Pieter CornillieDepartment of Morphology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Jimmy H SaundersDepartment of Veterinary Medical Imaging and Small Animal Orthopaedics, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Jaco BakkerDepartment of Animal Science Department, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Jan A M LangermansDepartment of Animal Science Department, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Christophe CasteleynDepartment of Morphology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium; Department of Veterinary Sciences, Faculty of Pharmaceutical, Bio-chemical and Veterinary Sciences, University of Antwerp, Wilrijk, Belgium.
Annemie DecostereDepartment of Morphology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Koen ChiersDepartment of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Ghent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over several years, 0% to 5% of adolescent animals in a captive colony of common marmosets (Callithrix jacchus) showed severely bended arms and legs over several years. The animals showed no pain, discomfort, or altered behavior but were unable to stretch their distal limbs to their full extent. To characterize the lesion morphologically, the bones of 4 affected marmosets were compared macroscopically and radiographically with those of 6 unaffected animals. The deformities were characterized by mid- to distal diaphyseal bending and pronounced shortening of long bones. The morphology and density of other bones including the skull and vertebrae were unaffected. Although vitamin D values were low in a fifth affected marmoset during 10 to 16 mo of age, lesions associated with rickets were not observed. To our knowledge, this report is the first to describe a micromelic dysplasia-like syndrome comprising severe, idiopathic bending and shortening of long bones in a colony of marmosets.

Indexed as

Animals, LaboratoryCallithrixAnimalsFemaleFemurMaleMonkey DiseasesOsteochondrodysplasiasParathyroid HormoneStatistics, NonparametricVitamin DParathyroid HormoneVitamin D

Identifiers

PMID25402180
PMCPMC4236788
OpenAlexW1452803831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.