SynthesisAnnals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists2014
Relapse prevention after index electroconvulsive therapy in treatment-resistant depression.
Synthesis in Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Relapse Following Electroconvulsive Therapy for Schizophrenia: A Systematic Review and Meta-analysis.Schizophrenia bulletin · 2026Pooled it
- Systematic review on relapse-prevention strategies following successful electroconvulsive therapy for major depressive disorder.BJPsych open · 2026Review
- Real-world analysis of pharmacological treatments to prevent relapse after electroconvulsive therapy for major depressive disorder: A nationwide cohort study.Translational psychiatry · 2025Article
- Accelerated Theta Burst Stimulation: Safety, Efficacy, and Future Advancements.Biological psychiatry · 2024Review
- The influence of concomitant antidepressant and antipsychotic medication on antidepressant effect and seizure duration of electroconvulsive therapy.Frontiers in psychiatry · 2024Article
- Electroconvulsive therapy combined with lithium developed reversible pure anomic aphasia: a case report.BMC psychiatry · 2022Article
- Double-Blinded Randomized Pilot Clinical Trial Comparing Cognitive Side Effects of Standard Ultra-Brief Right Unilateral ECT to 0.5 A Low Amplitude Seizure Therapy (LAP-ST).Brain sciences · 2020Article
- The Immediate Early GeneFrontiers in behavioral neuroscience · 2018Article
- Is Conduct of Research in Electroconvulsive Therapy Ethical?Journal of psychology, neuropsychiatric disorders and brain stimulation · 2016Article
- Perils of Pragmatic Psychiatry: How We Can Do Better.HSOA journal of psychiatry, depression & anxietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundOne-third of patients who suffer from depression are resistant to conventional treatments. An acute course of electroconvulsive therapy (ECT) can lead to remission of depressive symptoms in a substantial portion of the treatment-resistant patients. However, prevention of relapse with depressive symptoms after the index course of ECT can be challenging. We review pertinent studies on the topic and analyze the best strategies to avoid relapse and recurrence of depressive symptoms.
methodsWe performed a systematic literature review of PubMed through April 2014 for clinical trials published in English to determine if continuation ECT (C-ECT), continuation medication, continuation psychotherapy, or combinations of these are the best strategy to avoid relapse and recurrence of depressive symptoms after an acute course of ECT. Clinical trials comparing ≥2 of the above strategies were included in the review.
resultsAlthough there are few rigorous randomized clinical trials in this area, most studies suggest that combined C-ECT and continuation pharmacotherapy are the most effective strategy in relapse prevention.
conclusionsC-ECT and continuation pharmacotherapy may be more effective than either alone for preventing relapse. However, more definitive randomized clinical trials are needed.
Indexed as
Identifiers
25401716PMC4420179W2283249823What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.