ArticleMolecules (Basel, Switzerland)2014
Proteolysis, NaOH and ultrasound-enhanced extraction of anticoagulant and antioxidant sulfated polysaccharides from the edible seaweed, Gracilaria birdiae.
Article in Molecules (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 61 citations in OpenAlex.
- Review
- Antioxidant and Cytoprotective Effects of Chilean Macroalgae Against Oxidative Stress-Induced Damage in Gastric Epithelial Cells.Nutrients · 2026Article
- Alleviating effects of Gracilaria verrucosa supplement on non-specific immunity, antioxidant capacity and immune-related genes of pacific white shrimp (Litopenaeus vannamei) provoked with white spot syndrome virus.BMC veterinary research · 2024Article
- Sulfated Galactans from Agarophytes: Review of Extraction Methods, Structural Features, and Biological Activities.Biomolecules · 2023Review
- Nanotechnology-driven improvisation of red algae-derived carrageenan for industrial and bio-medical applications.World journal of microbiology & biotechnology · 2023Review
- A Blend Consisting of Agaran from SeaweedMarine drugs · 2023Article
- Biochemical Characteristics and Potential Biomedical Applications of Hydrolyzed Carrageenans.Marine drugs · 2023Article
- Optimization of R-Phycoerythrin Extraction by Ultrasound-Assisted Enzymatic Hydrolysis: A Comprehensive Study on the Wet SeaweedMarine drugs · 2023Article
- Biological properties and potential of compounds extracted from red seaweeds.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2022Review
- Article
- In Vitro and In Vivo Antioxidant Activity ofBiomolecules · 2020Article
- Antioxidant Sulfated Polysaccharide from Edible Red SeaweedMolecules (Basel, Switzerland) · 2020Article
- Integral Utilization of Red Seaweed for Bioactive Production.Marine drugs · 2019Review
- Oligosaccharides Derived from Red Seaweed: Production, Properties, and Potential Health and Cosmetic Applications.Molecules (Basel, Switzerland) · 2018Review
- Article
- Dietary supplementation of heat-treatedBiology open · 2017Article
- Structural Characteristics and Antioxidant Activities of Fucoidans from Five Brown Seaweeds.Journal of applied glycoscience · 2016Article
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Authors and funding
7 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The sulfated polysaccharides (SP) from the edible red seaweed, Gracilaria birdiae, were obtained using five different extraction conditions: Gracilaria birdiae 1 (GB1)-water; GB1s-water/sonication; GB1sp-water/sonication/proteolysis; GB2s-NaOH/sonication; and GB2sp-NaOH/sonication/proteolysis. The yield (g) increased in the following order: GB2sp>GB1sp>GB2s>GB1s>GB1. However, the amount of SP extracted increased in a different way: GB2sp>GB1>GB1sp>GB1s>GB2s. Infrared and electrophoresis analysis showed that all conditions extracted the same SP. In addition, monosaccharide composition showed that ultrasound promotes the extraction of polysaccharides other than SP. In the prothrombin time (PT) test, which evaluates the extrinsic coagulation pathway, none of the samples showed anticoagulant activity. While in the activated partial thromboplastin time (aPTT) test, which evaluates the intrinsic coagulation pathway, all samples showed anticoagulant activity, except GB2s. The aPTT activity decreased in the order of GB1sp>GB2sp>GB1>GB1s>GB2s. The total capacity antioxidant (TCA) of the SP was also affected by extraction condition, since GB2s and GB1 showed lower activity in comparison to the other conditions. In conclusion, the conditions of SP extraction influence their biological activities and chemical composition. The data revealed that NaOH/sonication/proteolysis was the best condition to extract anticoagulant and antioxidant SPs from Gracilaria birdiae.
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