Trial reportJournal of the Royal Society, Interface2014
Homological scaffolds of brain functional networks.
Trial report in Journal of the Royal Society, Interface, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 163 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
163 citing papers in PubMed, 660 citations in OpenAlex.
- Acute effects of different types of cannabis on young adult and adolescent resting-state brain networks.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Trial
- Distance-dependent connectivity in the brain facilitates high dynamical and structural complexity.Cognitive neurodynamics · 2026Article
- Structure Guides Function: Beyond Pairwise Neural Interactions.The Journal of comparative neurology · 2026Review
- Article
- Charting higher-order models of brain function beyond pairwise interactions.Nature communications · 2026Article
- Phase locking and multistability in the topological Kuramoto model on cell complexes.Nature communications · 2026Article
- Developing Methods for Observing Awe Narration in Psilocybin-Assisted Therapy.Healthcare (Basel, Switzerland) · 2026Article
- Chordless cycle filtrations for dimensionality detection in complex networks via topological data analysis.Nature communications · 2026Article
- Global topology of brain-wide co-fluctuations links task states, personality, and behavioral symptom dimensions.bioRxiv : the preprint server for biology · 2026Article
- Higher-order functional connectivity and topological analysis of multichannel fNIRS data.Biomedical optics express · 2026Article
- High-Order Interactions Reshape the Carbon Emission Efficiency Network Across Chinese Regions.Entropy (Basel, Switzerland) · 2026Article
- Structural signatures of synergy and redundancy in human brain function.bioRxiv : the preprint server for biology · 2026Article
- Node persistence from topological data analysis reveals changes in brain functional connectivity.Patterns (New York, N.Y.) · 2026Article
- A Blueprint for Implementing Ketamine-Assisted Psychotherapy in Palliative Care: Design, Process, and Treatment Patterns of a Real-World Clinical Program.Journal of palliative medicine · 2026Article
- Reducibility of higher-order networks from dynamics.Nature communications · 2026Article
- The microscale organization of directed hypergraphs.Communications physics · 2026Article
- Dissociable effects of LSD and MDMA on striato-cortical connectivity in healthy subjects.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Neurobiological Correlates of Psychedelic Experiences and Psychedelic-Associated Adverse Effects.Current topics in behavioral neurosciences · 2026Review
- Psilocybin: clinical potential, mechanistic insights, and biotechnological advances for scalable production.World journal of microbiology & biotechnology · 2025Review
- The topology of synergy: Linking topological and information-theoretic approaches to higher-order interactions in complex systems.PLoS computational biology · 2025Article
103 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Networks, as efficient representations of complex systems, have appealed to scientists for a long time and now permeate many areas of science, including neuroimaging (Bullmore and Sporns 2009 Nat. Rev. Neurosci. 10, 186-198. (doi:10.1038/nrn2618)). Traditionally, the structure of complex networks has been studied through their statistical properties and metrics concerned with node and link properties, e.g. degree-distribution, node centrality and modularity. Here, we study the characteristics of functional brain networks at the mesoscopic level from a novel perspective that highlights the role of inhomogeneities in the fabric of functional connections. This can be done by focusing on the features of a set of topological objects-homological cycles-associated with the weighted functional network. We leverage the detected topological information to define the homological scaffolds, a new set of objects designed to represent compactly the homological features of the correlation network and simultaneously make their homological properties amenable to networks theoretical methods. As a proof of principle,we apply these tools to compare resting state functional brain activity in 15 healthy volunteers after intravenous infusion of placebo and psilocybin-the main psychoactive component of magic mushrooms. The results show that the homological structure of the brain's functional patterns undergoes a dramatic change post-psilocybin, characterized by the appearance of many transient structures of low stability and of a small number of persistent ones that are not observed in the case of placebo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.