ArticleBiomedical optics express2014
A high-efficiency fiber-based imaging system for co-registered autofluorescence and optical coherence tomography.
Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03285841 (Co-registered Multimodal Optical Imaging for the Early Detection and Management of Cancers of the Vulva and Cervix), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Co-registered Multimodal Optical Imaging for the Early Detection and Management of Cancers of the Vulva and Cervix
Who cites it
21 citing papers in PubMed.
- Sensor-integrated dual-clad fiber probe for OCT-guided retinal endolaser photocoagulation.Journal of biomedical optics · 2026Article
- Quantification and mitigation of system background fluorescence in fiber-optic-based imaging systems.Biomedical optics express · 2026Article
- Segmental airway adenocarcinoma-simulating phantom for endoscopic near-infrared optical coherence tomography.Journal of biomedical optics · 2025Article
- Identification and removal of system-induced autofluorescence in miniaturized fiber-optic fluorescence endoscopes.PNAS nexus · 2025Article
- Multimodal Optical Imaging of Ex Vivo Fallopian Tubes to Distinguish Early and Occult Tubo-Ovarian Cancers.Cancers · 2024Article
- Ex vivo optical coherence tomography combined with near infrared targeted fluorescence: towardsBiomedical optics express · 2024Article
- The LMIT: Light-mediated minimally-invasive theranostics in oncology.Theranostics · 2024Review
- EndoscopicBiomedical optics express · 2022Article
- Double-Clad Fiber-Based Multifunctional Biosensors and Multimodal Bioimaging Systems: Technology and Applications.Biosensors · 2022Review
- Dual-modality optical coherence tomography and fluorescence tethered capsule endomicroscopy.Biomedical optics express · 2021Article
- Long-range optical coherence tomography with extended depth-of-focus: a visual feedback system for smart laser osteotomy.Biomedical optics express · 2021Article
- Submillimeter diameter rotary-pullback fiber-optic endoscope for narrowband red-green-blue reflectance, optical coherence tomography, and autofluorescence in vivo imaging.Journal of biomedical optics · 2019Article
- En-face optical coherence tomography/fluorescence endomicroscopy for minimally invasive imaging using a robotic scanner.Journal of biomedical optics · 2019Article
- High resolution combined molecular and structural optical imaging of colorectal cancer in a xenograft mouse model.Biomedical optics express · 2018Article
- Noninvasive structural and microvascular anatomy of oral mucosae using handheld optical coherence tomography.Biomedical optics express · 2017Article
- Simultaneous, label-free, multispectral fluorescence lifetime imaging and optical coherence tomography using a double-clad fiber.Optics letters · 2017Article
- Method for single illumination source combined optical coherence tomography and fluorescence imaging of fluorescently labeled ocular structures in transgenic mice.Experimental eye research · 2016Article
- Endoscopic Doppler optical coherence tomography and autofluorescence imaging of peripheral pulmonary nodules and vasculature.Biomedical optics express · 2015Article
- Molecular imaging needles: dual-modality optical coherence tomography and fluorescence imaging of labeled antibodies deep in tissue.Biomedical optics express · 2015Article
- Laser tissue coagulation and concurrent optical coherence tomography through a double-clad fiber coupler.Biomedical optics express · 2015Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a power-efficient fiber-based imaging system capable of co-registered autofluorescence imaging and optical coherence tomography (AF/OCT). The system employs a custom fiber optic rotary joint (FORJ) with an embedded dichroic mirror to efficiently combine the OCT and AF pathways. This three-port wavelength multiplexing FORJ setup has a throughput of more than 83% for collected AF emission, significantly more efficient compared to previously reported fiber-based methods. A custom 900 µm diameter catheter ‒ consisting of a rotating lens assembly, double-clad fiber (DCF), and torque cable in a stationary plastic tube ‒ was fabricated to allow AF/OCT imaging of small airways in vivo. We demonstrate the performance of this system ex vivo in resected porcine airway specimens and in vivo in human on fingers, in the oral cavity, and in peripheral airways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.