Evidence map›Paper›PMID 25400934›Full record

ArticleJournal of materials chemistry. B2014

Solid phase synthesis of functionalised SAM-forming alkanethiol-oligoethyleneglycols.

James Murray, Dominika Nowak, Laurynas Pukenas, Rizuan Azhar, Mathieu Guillorit, Christoph Wälti, Kevin Critchley, Steven Johnson, Robin S Bon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of materials chemistry. B, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Small-Molecule Patterning via Prefunctionalized Alkanethiols.Chemistry of materials : a publication of the American Chemical Society · 2018
    Article
  2. The electrophotonic silicon biosensor.Nature communications · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

James MurraySchool of Chemistry, University of Leeds, LS2 9JT, UK ; Astbury Centre for Structural Molecular Biology, University of Leeds, UK.
Dominika NowakAstbury Centre for Structural Molecular Biology, University of Leeds, UK ; School of Electronic and Electrical Engineering, University of Leeds, UK.
Laurynas PukenasAstbury Centre for Structural Molecular Biology, University of Leeds, UK ; School of Physics and Astronomy, University of Leeds, UK.
Rizuan AzharDepartment of Electronics, University of York, Heslington York, YO10 5DD, UK.
Mathieu GuilloritSchool of Chemistry, University of Leeds, LS2 9JT, UK.
Christoph WältiSchool of Electronic and Electrical Engineering, University of Leeds, UK.
Kevin CritchleyAstbury Centre for Structural Molecular Biology, University of Leeds, UK ; School of Physics and Astronomy, University of Leeds, UK.
Steven JohnsonDepartment of Electronics, University of York, Heslington York, YO10 5DD, UK.
Robin S BonSchool of Chemistry, University of Leeds, LS2 9JT, UK ; Astbury Centre for Structural Molecular Biology, University of Leeds, UK.

Funding

Wellcome Trust 088908
6 · The paper itself

Abstract

We present an efficient solid phase synthesis methodology that provides easy access to a range of functionalised long-chain alkanethiol-oligoethyleneglycols that form well-defined self-assembled monolayers on gold and are compatible with pre- or post-assembly conjugation of (bio)molecules. We demonstrate the versatility of our synthetic route by synthesising LCAT-OEGs with a range of functional moieties, including peptides, electro-active redox groups, chemical handles for post-assembly conjugation of (bio)molecules, and demonstrate the application of our LCAT-OEG monolayers in immunosensing, where they show good biocompatibility with minimal biofouling.

Identifiers

PMID25400934
PMCPMC4229624

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.