ReviewCell & bioscience2014
Recent advances in hydrogen peroxide imaging for biological applications.
Review in Cell & bioscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 111 citations in OpenAlex.
- Prussian blue nanofilm-sensitized plasmonic electrochemical microscopy for spatially resolved detection of the localized delivery of hydrogen peroxide.Sensors and actuators reports · 2024Article
- Dye-Decolorizing Peroxidases Maintain High Stability and Turnover on Kraft Lignin and Lignocellulose Substrates.ACS omega · 2024Article
- Hydrogen peroxide responsive theranostics for cancer-selective activation of DNA alkylators and real-time fluorescence monitoring in living cells.European journal of medicinal chemistry · 2024Article
- Recent Development of Lysosome-Targeted Organic Fluorescent Probes for Reactive Oxygen Species.Molecules (Basel, Switzerland) · 2023Review
- Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications.Nanoscale advances · 2023Review
- Delivery of Lipid Nanoparticles with ROS Probes for Improved Visualization of Hepatocellular Carcinoma.Biomedicines · 2023Article
- Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer's Disease.ACS applied materials & interfaces · 2023Review
- Tumor-targeted bioactive nanoprobes visualizing of hydrogen peroxide for forecasting chemotherapy-exacerbated malignant prognosis.Frontiers in bioengineering and biotechnology · 2023Article
- The Roadmap of Graphene-Based Sensors: Electrochemical Methods for Bioanalytical Applications.Biosensors · 2022Review
- Design and Characterization of HyperpolarizedACS sensors · 2022Article
- SERS and Indicator Paper Sensing of Hydrogen Peroxide Using Au@Ag Nanorods.Sensors (Basel, Switzerland) · 2022Article
- Targeted contrast agents and activatable probes for photoacoustic imaging of cancer.Chemical Society reviews · 2022Review
- Evaluation of borinic acids as new, fast hydrogen peroxide-responsive triggers.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- MACA Fast and Efficient Method for Detecting HACS omega · 2021Article
- Solid State Sensors for Hydrogen Peroxide Detection.Biosensors · 2020Review
- A Comparative Study on the Oxidation of Label-Free Silver Triangular Nanoplates by Peroxides: Main Effects and Sensing Applications.Sensors (Basel, Switzerland) · 2020Article
- Assessing the range of enzymatic and oxidative tunability for biosensor design.Journal of materials chemistry. B · 2020Review
- Developing a Silk Fibroin Composite Film to Scavenge and Probe HSensors (Basel, Switzerland) · 2020Article
- Lignin biosynthesis: old roads revisited and new roads explored.Open biology · 2019Review
- Research progress in the development of organic small molecule fluorescent probes for detecting HRSC advances · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Mounting evidence supports the role of hydrogen peroxide (H2O2) in physiological signaling as well as pathological conditions. However, the subtleties of peroxide-mediated signaling are not well understood, in part because the generation, degradation, and diffusion of H2O2 are highly volatile within different cellular compartments. Therefore, the direct measurement of H2O2 in living specimens is critically important. Fluorescent probes that can detect small changes in H2O2 levels within relevant cellular compartments are important tools to study the spatial dynamics of H2O2. To achieve temporal resolution, the probes must also be photostable enough to allow multiple readings over time without loss of signal. Traditional fluorescent redox sensitive probes that have been commonly used for the detection of H2O2 tend to react with a wide variety of reactive oxygen species (ROS) and often suffer from photostablilty issues. Recently, new classes of H2O2 probes have been designed to detect H2O2 with high selectivity. Advances in H2O2 measurement have enabled biomedical scientists to study H2O2 biology at a level of precision previously unachievable. In addition, new imaging techniques such as two-photon microscopy (TPM) have been employed for H2O2 detection, which permit real-time measurements of H2O2 in vivo. This review focuses on recent advances in H2O2 probe development and optical imaging technologies that have been developed for biomedical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.