ReviewWorld journal of gastrointestinal endoscopy2014
Nodular lymphoid hyperplasia in the gastrointestinal tract in adult patients: A review.
Review in World journal of gastrointestinal endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 116 citations in OpenAlex.
- Nodular lymphoid hyperplasia in atypical SCID due to IL7R mutations mimicking CVID.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- The Cross-Knit Between Immune Cells and Thyroid Function in Autoimmune Thyroid Disorders: What We Can Learn from Inborn Errors of Immunity.Children (Basel, Switzerland) · 2026Review
- Gastrointestinal Manifestations of Common Variable Immunodeficiency: A Mentored Review.Digestive diseases and sciences · 2025Review
- Improved Survival From Graft-versus-host Disease Following Pediatric Small Intestinal Transplantation Through Reduction in Systemic Immunosuppression Altering T-cell Chimerism Dynamics.Transplantation direct · 2025Article
- Navigating the Complexities of Common Variable Immunodeficiency Enteropathy: From Established Therapies to Emerging Interventions.Immunology and allergy clinics of North America · 2025Review
- Gastrointestinal Disease in Common Variable Immunodeficiency Disorder (CVID): Histological Patterns, Diagnostic Clues and Pitfalls for the Pathologist and Gastroenterologist.Journal of clinical medicine · 2025Article
- Diagnostic Value of Ileal Lesions Found during Colonoscopy with Reference to Endoscopic Indications and Findings.Journal of clinical medicine · 2024Article
- Flexible Sigmoidoscopy Utility in the Diagnosis of Pediatric Gastrointestinal Disorders.Cureus · 2023Article
- The Importance of Endoscopy with Biopsy: Real-World Evidence of Gastrointestinal Involvement in Primary Immunodeficiency in Two Main Northern Italian Centres.Biomedicines · 2023Article
- Article
- Mucosal bacterial dysbiosis in patients with nodular lymphoid hyperplasia in the terminal ileum.World journal of gastroenterology · 2022Article
- Multisystem Autoimmune Inflammatory Disease, Including Colitis, Due to Inborn Error of Immunity.Pediatrics · 2021Article
- Evaluation of Morphological and Histological Changes of Aggregated Lymph Nodes in the Small Intestine after Imofan Treatment in Immunosuppressed Rats.Archives of Razi Institute · 2021Article
- Graft Versus Host Disease After Intestinal Transplantation: A Single-center Experience.Transplantation direct · 2021Article
- Granulomatous-Lymphocytic Interstitial Lung Disease Mimicking Sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2021Article
- Case Report: Intestinal Nodular Lymphoid Hyperplasia as First Manifestation of Activated PI3Kδ Syndrome Due to a NovelFrontiers in pediatrics · 2021Article
- Duodenal nodular lymphoid hyperplasia in a patient with IgA deficiency.Clinical case reports · 2020Article
- Kyoto classification in patients who developed multiple gastric carcinomas afterWorld journal of gastrointestinal endoscopy · 2020Article
- The Epidemiology and Clinical Manifestations of Autoimmunity in Selective IgA Deficiency.Clinical reviews in allergy & immunology · 2020Review
- Ileocolonic Lymphonodular Hyperplasia in Children Related to Etiologies Ranging from Food Hypersensitivity to Familial Mediterranean Fever.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nodular lymphoid hyperplasia of the gastrointestinal tract is characterized by the presence of multiple small nodules, normally between between 2 and 10 mm in diameter, distributed along the small intestine (more often), stomach, large intestine, or rectum. The pathogenesis is largely unknown. It can occur in all age groups, but primarily in children and can affect adults with or without immunodeficiency. Some patients have an associated disease, namely, common variable immunodeficiency, selective IgA deficiency, Giardia infection, or, more rarely, human immunodeficiency virus infection, celiac disease, or Helicobacter pylori infection. Nodular lymphoid hyperplasia generally presents as an asymptomatic disease, but it may cause gastrointestinal symptoms like abdominal pain, chronic diarrhea, bleeding or intestinal obstruction. A diagnosis is made at endoscopy or contrast barium studies and should be confirmed by histology. Its histological characteristics include markedly hyperplasic, mitotically active germinal centers and well-defined lymphocyte mantles found in the lamina propria and/or in the superficial submucosa, distributed in a diffuse or focal form. Treatment is directed towards associated conditions because the disorder itself generally requires no intervention. Nodular lymphoid hyperplasia is a risk factor for both intestinal and, very rarely, extraintestinal lymphoma. Some authors recommend surveillance, however, the duration and intervals are undefined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.