Evidence map›Paper›PMID 25400794›Full record

ReviewInternational journal of clinical and experimental pathology2014

HIV-related Burkitt lymphoma with florid granulomatous reaction: an unusual case with good outcome.

Jin-Nan Li, Li-Min Gao, Wei-Ya Wang, Min Chen, Gan-Di Li, Wei-Ping Liu, Wen-Yan Zhang

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. The clinicopathologic spectrum of mature aggressive B cell lymphomas.Virchows Archiv : an international journal of pathology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jin-Nan LiDepartment of Pathology, West China Hospital, Sichuan University Chengdu 610041, China.
Li-Min GaoDepartment of Pathology, West China Hospital, Sichuan University Chengdu 610041, China.
Wei-Ya WangDepartment of Pathology, West China Hospital, Sichuan University Chengdu 610041, China.
Min ChenDepartment of Pathology, West China Hospital, Sichuan University Chengdu 610041, China.
Gan-Di LiDepartment of Pathology, West China Hospital, Sichuan University Chengdu 610041, China.
Wei-Ping LiuDepartment of Pathology, West China Hospital, Sichuan University Chengdu 610041, China.
Wen-Yan ZhangDepartment of Pathology, West China Hospital, Sichuan University Chengdu 610041, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burkitt lymphoma (BL) is a highly aggressive subtype of non-Hodgkin lymphomas (NHL). Lymphoma related granulomatous reaction rarely occurs in sporadic BL. Herein, we describe the first case of HIV related Burkitt lymphoma with florid granulomatous reaction. A 41-year-old HIV-positive Chinese male presented lymphadenopathy in the right cervical region for 3 months. The enlarged lymph node biopsies revealed the presence of prominent granulomas of varying size with Langhans giant cells, leading to the misdiagnosis of tuberculous lymphadenitis in other hospital. Subsequently, the case was sent to us for consultation. The morphology, immunophenotype, special staining, interphase FISH analysis and blood tests confirmed a diagnosis of HIV related Burkitt lymphoma with granulomatous reaction. Without radiotherapy and chemotherapy, the patient was alive and well with no evidence of lymphoma during the observation period of 24 months. The case suggested that lymphoma with florid granulomatous reaction can easily be misdiagnosed as benign lesions since the large number of epithelioid granulomas could obscure the primary lesion. Moreover, the granulomatous reaction may be an indicator for favorable prognosis in HIV related Burkitt lymphoma.

Indexed as

AdultBiomarkers, TumorBiopsyBurkitt LymphomaDiagnostic ErrorsGranulomaHIV InfectionsHumansImmunohistochemistryIn Situ Hybridization, FluorescenceLymph Node ExcisionLymph NodesMalePredictive Value of TestsTuberculosis, Lymph NodeBiomarkers, Tumorgranulomatous reactionHuman immunodeficiency virus related Burkitt lymphomaprognosis

Identifiers

PMID25400794
PMCPMC4230138
OpenAlexW341637811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.