ArticleThe open biomedical engineering journal2014
Reality of dental implant surface modification: a short literature review.
Article in The open biomedical engineering journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03854162 (The Accuracy of Partially or Fully Guided Dental Implantation Performed With Dental Implantological Surgical Guide as Compared to Freehand Dental Implantation), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Accuracy of Partially or Fully Guided Dental Implantation Performed With Dental Implantological Surgical Guide as Compared to Freehand Dental Implantation
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Bridging the missing middle in osseointegration: meso-scale topography between macro design and microroughness.International journal of implant dentistry · 2025Pooled it
- Pooled it
- The Effect of Er:YAG Laser Biomodification of the Implant Site Surface on Osseointegration: A Randomized Controlled Clinical Study.Journal of functional biomaterials · 2026Article
- Influence of Micro-Nanostructured Anatase-Coated SLA Titanium on Macrophage Behavior.Journal of functional biomaterials · 2026Article
- Beyond microroughness: novel approaches to navigate osteoblast activity on implant surfaces.International journal of implant dentistry · 2024Review
- Nanofeatured surfaces in dental implants: contemporary insights and impending challenges.International journal of implant dentistry · 2024Review
- Biological Performance of Titanium Surfaces with Different Hydrophilic and Nanotopographical Features.Materials (Basel, Switzerland) · 2023Article
- Vapor-Induced Pore-Forming Atmospheric-Plasma-Sprayed Zinc-, Strontium-, and Magnesium-Doped Hydroxyapatite Coatings on Titanium Implants Enhance New Bone Formation-An In Vivo and In Vitro Investigation.International journal of molecular sciences · 2023Article
- Overview of strategies to improve the antibacterial property of dental implants.Frontiers in bioengineering and biotechnology · 2023Review
- HowMaterials (Basel, Switzerland) · 2022Review
- Hyaluronic Acid-Based Nanomaterials as a New Approach to the Treatment and Prevention of Bacterial Infections.Frontiers in bioengineering and biotechnology · 2022Review
- Effect of microtopography on osseointegration of implantable biomaterials and its modification strategies.Frontiers in bioengineering and biotechnology · 2022Review
- In Vivo and In Vitro Analyses of Titanium-Hydroxyapatite Functionally Graded Material for Dental Implants.BioMed research international · 2021Article
- Modifications of Dental Implant Surfaces at the Micro- and Nano-Level for Enhanced Osseointegration.Materials (Basel, Switzerland) · 2019Review
- Accentuated osseointegration in osteogenic nanofibrous coated titanium implants.Scientific reports · 2019Article
- Osteogenic Cell Behavior on Titanium Surfaces in Hard Tissue.Journal of clinical medicine · 2019Article
- A Clue to the Existence of Bonding between Bone and Implant Surface: An In Vivo Study.Materials (Basel, Switzerland) · 2019Article
- Bone-Healing Pattern on the Surface of Titanium Implants at Cortical and Marrow Compartments in Two Topographic Sites: an Experimental Study in Rabbits.Materials (Basel, Switzerland) · 2018Article
- Engineered Coatings for Titanium Implants To Present Ultralow Doses of BMP-7.ACS biomaterials science & engineering · 2018Article
- Micro/nano hierarchical structured titanium treated by NH4OH/H2O2 for enhancing cell response.PloS one · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Screw-shaped endosseous implants that have a turned surface of commercially pure titanium have a disadvantage of requiring a long time for osseointegration while those implants have shown long-term clinical success in single and multiple restorations. Titanium implant surfaces have been modified in various ways to improve biocompatibility and accelerate osseointegration, which results in a shorter edentulous period for a patient. This article reviewed some important modified titanium surfaces, exploring the in vitro, in vivo and clinical results that numerous comparison studies reported. Several methods are widely used to modify the topography or chemistry of titanium surface, including blasting, acid etching, anodic oxidation, fluoride treatment, and calcium phosphate coating. Such modified surfaces demonstrate faster and stronger osseointegration than the turned commercially pure titanium surface. However, there have been many studies finding no significant differences in in vivo bone responses among the modified surfaces. Considering those in vivo results, physical properties like roughening by sandblasting and acid etching may be major contributors to favorable bone response in biological environments over chemical properties obtained from various modifications including fluoride treatment and calcium phosphate application. Recently, hydrophilic properties added to the roughened surfaces or some osteogenic peptides coated on the surfaces have shown higher biocompatibility and have induced faster osseointegration, compared to the existing modified surfaces. However, the long-term clinical studies about those innovative surfaces are still lacking.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.