ArticleDiabetology & metabolic syndrome2014
Supplementary use of HbA1c as hyperglycemic criterion to detect metabolic syndrome.
Article in Diabetology & metabolic syndrome, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Profile and predictors of metabolic syndrome among young adults attending a Medical College in Quetta City, Pakistan.Journal of pharmaceutical policy and practice · 2026Article
- Sustained metabolic dysregulation and the emergence of diabetes: associations between HbA1c and metabolic syndrome components in Tunisian diabetic and nondiabetic groups.Journal of physiological anthropology · 2024Article
- Emergency Medical Services Clinicians Have a High Prevalence of Metabolic Syndrome.Prehospital emergency care · 2023Review
- Metabolic Syndrome in Fasting and Non-Fasting Participants: The UAE Healthy Future Study.International journal of environmental research and public health · 2022Article
- Prediction of metabolic and pre-metabolic syndromes using machine learning models with anthropometric, lifestyle, and biochemical factors from a middle-aged population in Korea.BMC public health · 2022Article
- The relationship between high-density lipoprotein cholesterol (HDL-C) and glycosylated hemoglobin in diabetic patients aged 20 or above: a cross-sectional study.BMC endocrine disorders · 2021Article
- Interaction of Adiponectin Genotypes and Insulin Resistance on the Occurrence of Taiwanese Metabolic Syndrome.BioMed research international · 2021Article
- Population-derived cut-off for HbA1c could enhance the identification of metabolic syndrome among non-diabetic population.Heliyon · 2020Article
- Sex-Specific Associations Between Area-Level Poverty and Cardiometabolic Dysfunction Among US Adolescents.Public health reports (Washington, D.C. : 1974) · 2020Article
- Examining the relationship between body mass index and adverse cardio-metabolic profiles among Australian Indigenous and non-Indigenous young adults.Scientific reports · 2019Article
- Prevalence of metabolic syndrome and the comparison of fasting plasma glucose and HbA1c as the glycemic criterion for MetS definition in non-diabetic population in Ghana.Diabetology & metabolic syndrome · 2019Article
- Plasma Neuregulin 4 Levels Are Associated with Metabolic Syndrome in Patients Newly Diagnosed with Type 2 Diabetes Mellitus.Disease markers · 2018Article
- Using Routine Hemoglobin A1c Testing to Determine the Glycemic Status in Psychiatric Inpatients.Frontiers in endocrinology · 2017Article
- Article
- Association of Metabolic Syndrome with the Adiponectin to Homeostasis Model Assessment of Insulin Resistance Ratio.Mediators of inflammation · 2015Article
- Prevalence and correlates of metabolic syndrome among rural women in Mysore, India.Indian heart journalArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic syndrome (MetS) refers to a cluster of cardiovascular risk factors including hyperglycemia, dyslipidemia, abdominal obesity and hypertension. An effective detection of MetS not only reflects the prediction risk of diabetes mellitus and cardiovascular diseases but also helps to plan for management strategy which could reduce the healthcare burden of the society. This study aimed to compare the use of hemoglobin A1c (HbA1c) to fasting plasma glucose (FPG) as the hyperglycemic component in MetS diagnosis.
methodsWaist circumference, blood pressure, blood triglyceride, high-density lipoprotein (HDL)-cholesterol, FPG, and HbA1c were examined in 120 Hong Kong Chinese adults with MetS and 120 without MetS. After reviewing the subject basal characteristics, 11 of them were found with undiagnosed diabetes (FPG ≧7.0 mmol/L) and were excluded for further analysis.
resultsThe most prevalent MetS components among the included subjects were elevated systolic blood pressure and central obesity. Significant correlation relationships existed between FPG and HbA1c in both subject pools diagnosed with and without MetS (p < 0.001). The diagnostic rate of MetS using HbA1c was compared to FPG by the receiver operating characteristics (ROC) analysis which suggested an area under curve of 0.807 (95% CI: 0.727 to 0.887). The agreement was 90.7% in MetS-positive group with increased FPG as one of the criterion co-existed with elevated HbA1c. If including HbA1c as an additional criterion to FPG in the MetS diagnosis, 30 more participants in MetS-negative group would be MetS-positive leading to an increase in detection rate. Furthermore, 47 subjects (38 from MetS-positive group and 9 from MetS-negative group) were found having HbA1c ≧6.5%, who would have been diagnosed with diabetes based on the diagnostic criteria implemented by the Expert Group in 2009.
conclusionThese findings suggest that HbA1c enhances the detection of hyperglycemia for the diagnosis of MetS.
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