Evidence map›Paper›PMID 25400699›Full record

ArticleDiabetology & metabolic syndrome2014

Synergistic effects of neck circumference and metabolic risk factors on insulin resistance: the Cardiometabolic Risk in Chinese (CRC) study.

Jun Liang, Fei Teng, Xuekui Liu, Caiyan Zou, Yu Wang, Lianjun Dou, Zilin Sun, Lu Qi

Open access · goldAbstract read
In one paragraph

Article in Diabetology & metabolic syndrome, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jun LiangDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College; Affiliated Hospital of Southeast University, 199# South Jiefang Road, Xuzhou, 221009 Jiangsu China.
Fei TengDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College; Affiliated Hospital of Southeast University, 199# South Jiefang Road, Xuzhou, 221009 Jiangsu China.
Xuekui LiuDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College; Affiliated Hospital of Southeast University, 199# South Jiefang Road, Xuzhou, 221009 Jiangsu China.
Caiyan ZouDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College; Affiliated Hospital of Southeast University, 199# South Jiefang Road, Xuzhou, 221009 Jiangsu China.
Yu WangDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College; Affiliated Hospital of Southeast University, 199# South Jiefang Road, Xuzhou, 221009 Jiangsu China.
Lianjun DouDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College; Affiliated Hospital of Southeast University, 199# South Jiefang Road, Xuzhou, 221009 Jiangsu China.
Zilin SunInstitute of diabetes, Medical School, Southeast University, Nanjing, 210009 Jiangsu China.
Lu QiDepartment of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115 USA ; Department of Medicine, Channing Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115 USA.
Xuzhou Medical College · CNSoutheast University · CNXuzhou Central Hospital · CNHarvard University · US

Funding

Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI CORKEY, BARBARA E. · 1992 to 2021
$25.0M
Genetic Markers of CHD in Type 2 DiabetesR01HL071981 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI QI, LU · 2003 to 2012
$4.9M
Obesity Genes, Energy Regulation in Response to Weight-Loss DietsR01DK091718 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI QI, LU · 2012 to 2021
$4.5M
NHLBI NIH HHS R01 HL071981NIDDK NIH HHS P30 DK046200NIDDK NIH HHS R01 DK091718
6 · The paper itself

Abstract

objectivesRecent studies have associated neck circumference (NC) with insulin resistance (IR). We examined whether such relation was modified by other metabolic risk factors.

methodsThe study samples were from a community-based health examination survey in central China. A total of 2588 apparently healthy Chinese men and women were included.

resultsPlasma levels of total cholesterol (TC), HDL-C, uric acid (UA) and diastolic blood pressure (DBP) were independently associated with NC after adjusted for age, sex, body mass index (BMI), waist circumference (WC) and hip circumference (HC) (P = 0.009, 0.001, 0.015 and 0.015, respectively). We observed significant interactions of NC with triglyceride (TG) and UA (all the p for interaction = 0.001) in relation to HOMA-IR. It appeared that the associations between NC and HOMA-IR were more evident in those with higher UA or TG level.

conclusionsOur data indicate that in apparently healthy Chinese adults, there were synergistic effects of UA, TG and neck circumference on insulin resistance.

Indexed as

Insulin resistanceNeck circumferenceSynergistic effectsTriglycerideUric acid

Identifiers

PMID25400699
PMCPMC4232709
OpenAlexW2102705439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.