Evidence map›Paper›PMID 25400698›Full record

ArticleJournal of foot and ankle research2014

The associations of leg lean mass with foot pain, posture and function in the Framingham foot study.

Robert R McLean, Alyssa B Dufour, Patricia P Katz, Howard J Hillstrom, Thomas J Hagedorn, Marian T Hannan

Open access · goldAbstract read
In one paragraph

Article in Journal of foot and ankle research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Body Fat and Muscle Mass in Association with Foot Structure in Adolescents: A Cross-Sectional Study.International journal of environmental research and public health · 2020
    Article
  2. Article
  3. Leg Muscle Mass and Foot Symptoms, Structure, and Function: The Johnston County Osteoarthritis Project.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Robert R McLeanHebrew Senior Life Institute for Aging Research, Boston, MA USA ; Harvard Medical School, Boston, MA USA.
Alyssa B DufourHebrew Senior Life Institute for Aging Research, Boston, MA USA ; Harvard Medical School, Boston, MA USA.
Patricia P KatzUniversity of California, San Francisco, San Francisco, CA USA.
Howard J HillstromHospital for Special Surgery, New York, NY USA.
Thomas J HagedornHebrew Senior Life Institute for Aging Research, Boston, MA USA.
Marian T HannanHebrew Senior Life Institute for Aging Research, Boston, MA USA ; Harvard Medical School, Boston, MA USA.
Hebrew SeniorLife · USHarvard University · USHospital for Special Surgery · USUniversity of California, San Francisco · US

Funding

The Interplay of Sociodemographic and Genetic Factors in SLE Health DisparitiesP60AR053308 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YELIN, EDWARD H · 2006 to 2016
$11.8M
Foot Disorders, Pain and Physical Disability in EldersR01AR047853 · NIAMS · HEBREW REHABILITATION CENTER FOR AGED · PI HANNAN, MARIAN T. · 2002 to 2012
$5.1M
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS N01 HC025195NIAMS NIH HHS P60 AR053308NIAMS NIH HHS R01 AR047853
6 · The paper itself

Abstract

backgroundFoot disorders are common in older adults and associated with impaired lower extremity function. Reduced muscle mass may play a role in the etiology of foot disorders and consequent poor function.

methodsWe examined the association of leg lean mass with foot pain, posture and function among 1,795 individuals (mean age 67 years) from the population-based Framingham Foot Study (2002-2008). Pain was assessed via questionnaire, and a pressure mat classified foot posture (arch: high, low, referent) during standing and function (pronation, supination, referent) during gait. Leg lean mass was measured by whole body dual energy x-ray absorptiometry.

resultsIn age- and body mass index-adjusted logistic (pain) and multinomial logistic (posture, function) regression models, a 1-standard deviation increase in leg lean mass was associated with lower odds of foot pain (OR = 0.76, 95% CI: 0.68, 0.86) and pronation (OR = 0.76, 95% CI: 0.67, 0.85), and higher odds of supination (OR = 1.17, 95% CI: 1.04, 1.31). Adjustment for sex attenuated these associations. Higher leg lean mass was associated with lower odds of high arch, even after adjustment for sex (OR = 0.73, 95% CI: 0.60, 0.89).

conclusionsThough not related to foot pain or function, reduced leg lean mass was associated with extreme foot posture in older adults. Loss of muscle mass with aging may thus play a role in the etiology of functional impairment due to foot disorders.

Indexed as

Foot functionFoot painFoot structureLean massPopulation-based cohort

Identifiers

PMID25400698
PMCPMC4232671
OpenAlexW2109287217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.