Evidence map›Paper›PMID 25400462›Full record

ArticleWorld journal of gastroenterology2014

Magnifying endoscopy of gastric epithelial dysplasia based on the morphologic characteristics.

Hwa Mi Kang, Gwang Ha Kim, Do Youn Park, Hong Ryeol Cheong, Dong Hoon Baek, Bong Eun Lee, Geun Am Song

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Efforts to increase image quality during endoscopy: The role of pronase.World journal of gastrointestinal endoscopy · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hwa Mi KangHwa Mi Kang, Department of Internal Medicine, Busan Adeventist Hospital, Busan 602-819, South Korea.
Gwang Ha KimHwa Mi Kang, Department of Internal Medicine, Busan Adeventist Hospital, Busan 602-819, South Korea.
Do Youn ParkHwa Mi Kang, Department of Internal Medicine, Busan Adeventist Hospital, Busan 602-819, South Korea.
Hong Ryeol CheongHwa Mi Kang, Department of Internal Medicine, Busan Adeventist Hospital, Busan 602-819, South Korea.
Dong Hoon BaekHwa Mi Kang, Department of Internal Medicine, Busan Adeventist Hospital, Busan 602-819, South Korea.
Bong Eun LeeHwa Mi Kang, Department of Internal Medicine, Busan Adeventist Hospital, Busan 602-819, South Korea.
Geun Am SongHwa Mi Kang, Department of Internal Medicine, Busan Adeventist Hospital, Busan 602-819, South Korea.
Busan Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the difference in magnifying endoscopic findings of gastric epithelial dysplasias (GEDs) according to the morphologic characteristics.

methodsThis study included 46 GED lesions in 45 patients who underwent magnifying endoscopy using narrow band imaging (ME-NBI) before endoscopic resection. During ME-NBI, the microvascular and microsurface (MS) patterns and the presence of light blue crest (LBC) and white opaque substance were investigated. GEDs were categorized as adenomatous, foveolar, and hybrid types, and their mucin phenotype was evaluated.

resultsOf the 46 lesions, 27 (59%) were categorized as adenomatous, 15 (32%) as hybrid, and the remaining 4 (9%) as foveolar. All adenomatous GEDs showed the round pit and/or tubular MS patterns, all foveolar GEDs showed the papillary pattern, and hybrid GEDs showed mixed patterns (P < 0.001). LBC was more frequently observed in adenomatous GEDs than in hybrid or foveolar GEDs (52%, 33%, 0%, respectively), although this difference was not significant (P = 0.127). The papillary MS pattern was associated with MUC5AC and MUC6 expression, and the round pit and/or tubular MS patterns were associated with CD10 expression.

conclusionThe MS pattern in ME-NBI findings is useful for predicting the morphologic category and mucin phenotype of GEDs, and ME-NBI findings may guide decisions regarding GED treatment.

Indexed as

Image EnhancementNarrow Band ImagingAdenomaAgedAged, 80 and overBiomarkers, TumorEpithelial CellsFemaleGastric MucosaGastroscopyHumansImmunohistochemistryMaleMiddle AgedMucin 5ACMucin-6Biomarkers, TumorMUC5AC protein, humanMUC6 protein, humanMucin 5ACMucin-6NeprilysinDysplasiaMagnifying endoscopyMucinNarrow band imagingStomach

Identifiers

PMID25400462
PMCPMC4229543
OpenAlexW2049188209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.