Evidence map›Paper›PMID 25399418›Full record

ArticleNucleic acids research2015

The OMA orthology database in 2015: function predictions, better plant support, synteny view and other improvements.

Adrian M Altenhoff, Nives Škunca, Natasha Glover, Clément-Marie Train, Anna Sueki, Ivana Piližota, Kevin Gori, Bartlomiej Tomiczek, Steven Müller, Henning Redestig and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 223 citations in OpenAlex.

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  12. Plant-PathogenicmBio · 2023
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  14. Whole genome sequence and diversity in multigene families ofFrontiers in cellular and infection microbiology · 2023
    Article
  15. Defining the extent of gene function using ROC curvature.Bioinformatics (Oxford, England) · 2022
    Article
  16. Read2Tree: scalable and accurate phylogenetic trees from raw reads.bioRxiv : the preprint server for biology · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Adrian M AltenhoffUniversity College London, Gower Street, London WC1E 6BT, UK Swiss Institute of Bioinformatics, Universitätstr. 6, 8092 Zurich, Switzerland ETH Zurich, Computer Science, Universitätstr. 6, 8092 Zurich, Switzerland.
Nives ŠkuncaUniversity College London, Gower Street, London WC1E 6BT, UK Swiss Institute of Bioinformatics, Universitätstr. 6, 8092 Zurich, Switzerland ETH Zurich, Computer Science, Universitätstr. 6, 8092 Zurich, Switzerland.
Natasha GloverUniversity College London, Gower Street, London WC1E 6BT, UK Institut National de la Recherche Agronomique (INRA) UMR1095, Genetics, Diversity and Ecophysiology of Cereals, 5 Chemin de Beaulieu, 63039 Clermont-Ferrand, France Bayer CropScience NV, Technologiepark 38, 9052 Gent, Belgium.
Clément-Marie TrainETH Zurich, Computer Science, Universitätstr. 6, 8092 Zurich, Switzerland.
Anna SuekiUniversity College London, Gower Street, London WC1E 6BT, UK.
Ivana PiližotaUniversity College London, Gower Street, London WC1E 6BT, UK.
Kevin GoriEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Bartlomiej TomiczekUniversity College London, Gower Street, London WC1E 6BT, UK.
Steven MüllerUniversity College London, Gower Street, London WC1E 6BT, UK.
Henning RedestigBayer CropScience NV, Technologiepark 38, 9052 Gent, Belgium.
Gaston H GonnetSwiss Institute of Bioinformatics, Universitätstr. 6, 8092 Zurich, Switzerland ETH Zurich, Computer Science, Universitätstr. 6, 8092 Zurich, Switzerland.
Christophe DessimozUniversity College London, Gower Street, London WC1E 6BT, UK European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK c.dessimoz@ucl.ac.uk.
University College London · GBETH Zurich · CHBayer (Belgium) · BEEuropean Bioinformatics Institute · GBSIB Swiss Institute of Bioinformatics · CH

Funding

Biotechnology and Biological Sciences Research Council BB/L018241/1Wellcome Trust
6 · The paper itself

Abstract

The Orthologous Matrix (OMA) project is a method and associated database inferring evolutionary relationships amongst currently 1706 complete proteomes (i.e. the protein sequence associated for every protein-coding gene in all genomes). In this update article, we present six major new developments in OMA: (i) a new web interface; (ii) Gene Ontology function predictions as part of the OMA pipeline; (iii) better support for plant genomes and in particular homeologs in the wheat genome; (iv) a new synteny viewer providing the genomic context of orthologs; (v) statically computed hierarchical orthologous groups subsets downloadable in OrthoXML format; and (vi) possibility to export parts of the all-against-all computations and to combine them with custom data for 'client-side' orthology prediction. OMA can be accessed through the OMA Browser and various programmatic interfaces at http://omabrowser.org.

Indexed as

Databases, ProteinSequence Homology, Amino AcidAlgorithmsGene OntologyGenome, PlantHumansInternetPlant ProteinsProteomeSyntenyTriticumPlant ProteinsProteome

Identifiers

PMID25399418
PMCPMC4383958
OpenAlexW2004707197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.