Trial reportEuropean journal of applied physiology2015
Effects of vasodilatation and pressor response on neurovascular coupling during dynamic exercise.
Trial report in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Physiological influences on neurovascular coupling: A systematic review of multimodal imaging approaches and recommendations for future study designs.Experimental physiology · 2025Pooled it
- Exhaustive exercise attenuates the neurovascular coupling by blunting the pressor response to visual stimulation.BioMed research international · 2015Trial
- Temporal evolution of neurovascular coupling recovery following moderate- and high-intensity exercise.Physiological reports · 2021Article
- Effects of dominant and non-dominant passive arm manoeuvres on the neurovascular coupling response.European journal of applied physiology · 2017Article
- Neurovascular coupling in humans: Physiology, methodological advances and clinical implications.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeVisual stimulation increases the blood flow in the posterior cerebral artery (PCA), which supplies blood to the visual cortex by neurovascular coupling (NVC). Relative contributions of vasodilatation and pressor response on NVC during dynamic exercise are still unknown.
methodsWe measured the blood flow velocity in the PCA (PCAv) by transcranial Doppler ultrasound flowmetry during rest and exercise in 14 healthy males while they performed 12-min submaximal leg-cycle exercises at mild-, moderate-, and high-intensity, which corresponded to heart rates of 120, 140, and 160 bpm, respectively. NVC was estimated as the relative change in PCAv from 20 s eye-closing to the peak response during 40 s looking at a reversed checkerboard. Conductance index was calculated for evaluating vasodilatation as pressure divided by blood flow.
resultsIn response to visual stimulation, a magnitude of vasodilatation was significantly decreased under the moderate-intensity, while pressor response was significantly suppressed under the high-intensity exercises, compared with the control condition. Conversely, peak response to visual stimulation in PCAv was not affected by exercise intensity though relative and absolute responses were significantly lower in the moderate- and high-intensity exercises than the control.
conclusionIt is suggested that the contributions of pressor response and vasodilatation were modified by exercise intensity, partly playing a role for stabilizing the peak response of PCAv with visual stimulation during dynamic exercise.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.