Evidence map›Paper›PMID 25398681›Full record

ArticleTechnology in cancer research & treatment2015

Efficacy of the Dynamic Jaw Mode in Helical Tomotherapy With Static Ports for Breast Cancer.

Chikao Sugie, Yoshihiko Manabe, Akihiro Hayashi, Taro Murai, Taiki Takaoka, Yukiko Hattori, Hiromitsu Iwata, Ran Takenaka, Yuta Shibamoto

Abstract read
In one paragraph

Article in Technology in cancer research & treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
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  7. Helical tomotherapy for asymptomatic chemotherapy-refractory or -unfit multiple (3 or more) metastases.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chikao SugieDepartment of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan chikao@bg8.so-net.ne.jp.
Yoshihiko ManabeDepartment of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Akihiro HayashiDepartment of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan Department of Radiology, Okazaki City Hospital, Okazaki, Japan.
Taro MuraiDepartment of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Taiki TakaokaDepartment of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Yukiko HattoriDepartment of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan Department of Radiation Oncology, Nagoya Proton Therapy Center, Nagoya, Japan.
Hiromitsu IwataDepartment of Radiation Oncology, Nagoya Proton Therapy Center, Nagoya, Japan.
Ran TakenakaDepartment of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan Department of Radiology, Narita Memorial Hospital, Toyohashi, Japan.
Yuta ShibamotoDepartment of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recently developed dynamic jaw technology of tomotherapy can reduce craniocaudal dose spread without much prolonging the treatment time. This study aimed to investigate the efficacy of the dynamic jaw mode for tomotherapy of breast cancer. Static tomotherapy plans of the whole breast and supraclavicular regional lymph nodes, and plans for the whole breast only were generated in 25 patients with left-sided breast cancer. Plans with a field width of 2.5 or 5 cm with the dynamic or fixed jaw modes were made for each patient. The prescribed dose was 50 Gy in 25 fractions. In whole breast and supraclavicular nodal radiotherapy, dose distributions and homogeneity of the planning target volume (PTV) with the dynamic jaw mode were slightly inferior to those with the fixed jaw mode with a 5-cm field width (P < .05). However, lung low-dose volumes and mean doses of the larynx, thyroid, skin, and all the healthy tissues combined were smaller with the dynamic jaw mode than with the fixed jaw mode with a 5-cm field width (P < .001). In whole breast radiotherapy, mean doses of the skin and healthy tissues were lower with the dynamic jaw mode than with the fixed jaw mode with a 5-cm field width (P < .001) without significant differences in PTV dose distributions, homogeneity, and conformity. The dynamic jaw mode provided better sparing of organs at risks with minimal disturbance of dose-volume indices of PTV. Considering the treatment time, the 5-cm-field dynamic jaw mode is more efficient than the 2.5-cm fixed jaw mode.

Indexed as

Breast NeoplasmsFemaleHumansRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedTreatment Outcomebreast cancerdynamic jaw modestatic tomotherapy delivery

Identifiers

PMID25398681
PMCPMC4535315

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.