ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2015
Impact of body mass index on surgical outcomes after esophagectomy for patients with esophageal squamous cell carcinoma.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Prehabilitation Reduces Occurrence of Anastomotic Leaks After Esophagectomy-A Retrospective Cohort Analysis and Meta-analysis.Journal of gastrointestinal cancer · 2025Pooled it
- Effect of obesity on perioperative outcomes following gastrointestinal surgery: meta-analysis.BJS open · 2023Pooled it
- Impact of high body mass index on surgical outcomes and long-term survival among patients undergoing esophagectomy: A meta-analysis.Medicine · 2018Pooled it
- General Principles of Risk Mitigation before Colorectal Surgery.Clinics in colon and rectal surgery · 2026Review
- Comparison of Complications and Morbidity between Hand-Sewn and Stapled Anastomosis after Transhiatal Esophagectomy in Patients with Esophageal Cancer.Middle East journal of digestive diseases · 2025Article
- Long-term survival and risk factors in esophageal squamous cell carcinoma: A Kaplan-Meier and cox regression study.World journal of gastrointestinal surgery · 2024Article
- A narrative review of anastomotic leak in the Ivor Lewis esophagectomy: expected, accepted, but preventable.Translational cancer research · 2023Review
- Article
- Impact of Body Mass Index and Sarcopenia on Short- and Long-Term Outcomes After Esophageal Cancer Surgery: An Observational Study.Annals of surgical oncology · 2022Observational
- Prognostic Value of Body Mass Index Stratified by Alcohol Drinking Status in Patients With Esophageal Squamous Cell Carcinoma.Frontiers in oncology · 2022Article
- The prognostic impact of preoperative body mass index changes for patients with esophageal squamous cell carcinoma who underwent esophagectomy: A large-scale long-term follow-up cohort study.Frontiers in nutrition · 2022Article
- Factors Affecting Blood Loss During Thoracoscopic Esophagectomy for Esophageal Carcinoma.Journal of chest surgery · 2021Article
- Application of Machine Learning for Predicting Anastomotic Leakage in Patients with Gastric Adenocarcinoma Who Received Total or Proximal Gastrectomy.Journal of personalized medicine · 2021Article
- Use of vasopressors during esophagectomy is not associated with increased risk of anastomotic leak.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2021Article
- LYMPHOPARIETAL INDEX IN ESOPHAGEAL CANCER IS STRONGER THAN TNM STAGING IN LONG-TERM SURVIVAL PROGNOSIS IN A LATIN-AMERICAN COUNTRY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2021Article
- Clinical characteristics and survival of 5283 esophageal cancer patients: A multicenter study from eighteen hospitals across six regions in China.Cancer communications (London, England) · 2020Article
- Prognostic value of preoperative weight loss-adjusted body mass index on survival after esophagectomy for esophageal squamous cell carcinoma.World journal of gastroenterology · 2020Article
- Obesity as a surgical risk factor.Annals of gastroenterological surgery · 2018Review
- Association of Body Mass Index With Infectious Complications in Free Tissue Transfer for Head and Neck Reconstructive Surgery.JAMA otolaryngology-- head & neck surgery · 2017Article
- Influence of BMI on short-term surgical outcome after colorectal cancer surgery: a study based on the Swedish national quality registry.International journal of colorectal disease · 2015Article
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with overweight reportedly have more comorbidities, including diabetes mellitus and cardiovascular disease, and longer operating times as well as more blood loss during surgery compared with those with normal weight. However, the impact of overweight on the short-term outcome after transthoracic esophagectomy for patients with esophageal squamous cell carcinoma (ESCC) remains unclear. We hypothesized that overweight has a negative impact on short-term surgical outcomes after esophagectomy for patients with ESCC.
methodsA total of 304 patients who underwent transthoracic esophagectomy for ESCC were included in this study. Body mass index (BMI) was classified into three categories, <18.49, 18.50-24.99, and >25.00 (kg/m(2)), defined as low, normal, and high BMI, respectively, according to the World Health Organization criteria. We investigated the association of BMI status with patient demographics and surgical outcomes after esophagectomy for patients with ESCC. In addition, overall survival and relapse-free survival stratified by BMI were compared.
resultsFifty-nine (19.4 %) and 41 (13.4 %) patients were classified to low BMI and high BMI, respectively. The high-BMI group had significantly higher comorbidity rates of diabetes mellitus (p < 0.01) and anastomotic leakage (p = 0.011) than the normal-BMI group. There were no significant association between high BMI and another various complications except for an anastomotic leakage, severe complications defined by Clavien-Dindo classification and in-hospital mortality. In multivariate analysis, high BMI was a significant risk factor for anastomotic leakage (p = 0.030, hazard ratio; 3.423, 95%CI; 1.128-10.38). On the other hand, no significant association was observed between low BMI and short surgical outcomes. There were no significant differences in overall and relapse-free survival among the three BMI groups in univariate and multivariate analysis (p = 0.128 and p = 0.584, respectively).
conclusionThe surgical treatment should not be denied for patients with ESCC due to overweight and underweight. However, intraoperative prevention and postoperative careful monitoring for anastomotic leakage might be required after esophagectomy for overweight patients with ESCC.
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