Evidence map›Paper›PMID 25398378›Full record

ReviewCurrent neurology and neuroscience reports2015

An update and review of the treatment of myoclonus.

Kelly Mills, Zoltan Mari

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Movement disorders associated with diarrhoea.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  3. Adult-Onset Myoclonus: Comparisons and Contrasts in the Inpatient and Outpatient Settings.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
    Article
  4. Adult-Onset Myoclonus in a Large Urban Inpatient Setting: A Retrospective Cohort Study.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
    Article
  5. Myoclonus in older Cavalier King Charles Spaniels.Journal of veterinary internal medicine · 2022
    Article
  6. Myoclonus generators in sialidosis.Clinical neurophysiology practice · 2022
    Article
  7. A Comprehensive Review of Tic Disorders in Children.Journal of clinical medicine · 2021
    Review
  8. Physiology-Based Treatment of Myoclonus.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Review
  9. Review
  10. Myoclonic Disorders.Brain sciences · 2017
    Review
  11. Myoclonus- A Review.Annals of Indian Academy of Neurology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kelly MillsDepartment of Neurology, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Meyer 6-181D, Baltimore, MD, 21287, USA, Kmills16@jhmi.edu.
Zoltan Mari
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in medications and surgical therapy for neurological disorders may offer new therapeutic options for the treatment of myoclonus. Appropriate therapy for myoclonus depends on the etiology, and in some cases, myoclonus can improve when the provoking cause is eliminated. When the underlying cause for the movements is not immediately reversible, localization, disease pathophysiology, and etiology may each play a role in determining the most appropriate symptomatic treatment of disabling myoclonic jerks. While the use of many agents is still based on small, open-label case series and anecdotes, there is a growing body of evidence from head-to-head comparative trials in several types of myoclonus that may help guide therapy. New therapies for refractory myoclonus, including sodium oxybate and even deep brain stimulation, are also being explored with increasing enthusiasm.

Indexed as

HumansMyoclonus

Identifiers

PMID25398378
OpenAlexW2023505784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.