ReviewCurrent diabetes reports2015
Lifestyle therapy for the treatment of youth with type 2 diabetes.
Review in Current diabetes reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Preventing type 2 diabetes among Indigenous youth: A systematic review of community-based interventions.International journal of circumpolar health · 2024Pooled it
- Evaluation of the longitudinal change in health behavior profiles across treatment groups in the TODAY clinical trial.Pediatric diabetes · 2020 · on this mapTrial
- Impact of lifestyle behavior change on glycemic control in youth with type 2 diabetes.Pediatric diabetes · 2018 · on this mapTrial
- The effect of education in obese type 2 diabetes adolescents and young adults based on continuous glucose monitoring and smartwatch-derived lifelog data.Annals of pediatric endocrinology & metabolism · 2025Article
- Type 2 diabetes in children and adolescents: Exploring the disease heterogeneity and research gaps to optimum management.World journal of clinical pediatrics · 2024Review
- Challenges and pitfalls of youth-onset type 2 diabetes.World journal of diabetes · 2024Review
- The user-centered design and development of a childhood and adolescent obesity Electronic Health Record tool, a mixed-methods study.Frontiers in digital health · 2024Article
- From Metabolic Syndrome to Type 2 Diabetes in Youth.Children (Basel, Switzerland) · 2023Review
- Youth-onset type 2 diabetes mellitus: an urgent challenge.Nature reviews. Nephrology · 2023Review
- Honoring the voices of families: An interpretive description of parents' understandings of, and insights into preventing type 2 diabetes in adolescents.BMC pediatrics · 2022Article
- Article
- Anti-obesity pharmacotherapy for treatment of pediatric type 2 diabetes: Review of the literature and lessons learned from adults.Frontiers in endocrinology · 2022Review
- Worsening glycemic control in youth with type 2 diabetes during COVID-19.Frontiers in clinical diabetes and healthcare · 2022Article
- Role of exercise on insulin sensitivity and beta-cell function: is exercise sufficient for the prevention of youth-onset type 2 diabetes?Annals of pediatric endocrinology & metabolism · 2020Article
- The association of low-density lipoprotein cholesterol with elevated arterial stiffness in adolescents and young adults with type 1 and type 2 diabetes: The SEARCH for Diabetes in Youth study.Pediatric diabetes · 2020Article
- Adverse childhood experiences are associated with an increased risk of obesity in early adolescence: a population-based prospective cohort study.Pediatric research · 2019Article
- Heritability of Type 2 Diabetes in the Washington State Twin Registry.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019Article
- 'It's Important to Make Changes.' Insights about Motivators and Enablers of Healthy Lifestyle Modification from Young Aboriginal Men in Western Australia.International journal of environmental research and public health · 2019Article
- Physical activity for children with chronic disease; a narrative review and practical applications.BMC pediatrics · 2019Review
- Clinical and Psychosocial Factors Influencing Retinal Screening Uptake Among Young Adults with Type 2 Diabetes.Current diabetes reports · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type 2 diabetes (T2D) in youth is a relatively novel condition facing paediatric health care providers. Few experimental trials exist to guide clinical management in this population. Supporting and prescribing modifiable lifestyle behaviours is cornerstone in the management of T2D in adults. Clinical trials in obese adolescents suggest that intensive lifestyle interventions that include both dietary changes and increased physical activity elicit clinically meaningful reductions in weight and improve cardiovascular risk profiles. Observational studies in youth with T2D suggest that better diet quality and increased physical activity are associated with better metabolic control; however, the limited experimental data available does not support these observations. Trials evaluating lifestyle monotherapy for the treatment of hyperglycaemia in youth with T2D do not exist, and the only study evaluating combined lifestyle and pharmacologic therapy did not show additional benefit over pharmacologic treatment with metformin alone. Physiological and psychosocial differences between youth and adults with T2D likely contribute to the differences in the effectiveness of lifestyle therapy for improving glycaemic control. The current review describes these topics in detail and provides recommendations for paediatric health care providers for the promotion of lifestyle therapy for the management of hyperglycaemia and cardiovascular risk factors for youth with T2DM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.