ReviewMedicine2014
Myocarditis in adult-onset still disease.
Review in Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- Non-Classical Complications of Adult-Onset Still's Disease: A Multicenter Spanish Study.Journal of clinical medicine · 2025Article
- Multiorgan Dysfunction in a Patient With Adult-Onset Still's Disease Flare: A Case Report.Cureus · 2024Article
- Pregnancy-Associated Onset of Adult-Onset Still's Disease.AJP reports · 2024Review
- Article
- Article
- A rare presentation of acute myocarditis as a manifestation of adult-onset Still's disease: a case report.European heart journal. Case reports · 2023Article
- Fulminant myocarditis with adult-onset Still's disease: case-based review.Clinical rheumatology · 2023Review
- Article
- Cardiac Magnetic Resonance in Rheumatology to Detect Cardiac Involvement Since Early and Pre-clinical Stages of the Autoimmune Diseases: A Narrative Review.Frontiers in cardiovascular medicine · 2022Review
- Still's Disease Mortality Trends in France, 1979-2016: A Multiple-Cause-of-Death Study.Journal of clinical medicine · 2021Article
- Acute Myocarditis Revealing Adult-Onset Still's Disease.JACC. Case reports · 2021Article
- Characteristics and Clinical Value of 18F-FDG PET/CT in the Management of Adult-Onset Still's Disease: 35 Cases.Journal of clinical medicine · 2021Article
- COVID-19 gone bad: A new character in the spectrum of the hyperferritinemic syndrome?Autoimmunity reviews · 2020Review
- Myocarditis in Adult-Onset Still's Disease: Case-Based Review.Clinical rheumatology · 2020Review
- Adult-onset Still's disease revealed by a complete atrioventricular block, totally regressive under corticosteroid therapy.Journal of cardiology cases · 2020Article
- Still's Disease and Myopericarditis.Cureus · 2019Article
- Diagnostic and management of life-threatening Adult-Onset Still Disease: a French nationwide multicenter study and systematic literature review.Critical care (London, England) · 2018Article
- Cardiovascular disease in patients with autoinflammatory syndromes.Rheumatology international · 2018Review
- Article
- Cardiovascular Comorbidity in Inflammatory Rheumatological Conditions.Deutsches Arzteblatt international · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study highlights the clinical features, treatments, and outcomes of the rare myocarditis in adult-onset Still disease (AOSD). Among a case series of 57 patients fulfilling either Yamaguchi or Fautrel AOSD criteria and seen between 1998 and 2010, we identified 4 cases of myocarditis. From a comprehensive literature review, we collected 20 additional cases of myocarditis-complicated AOSD. The characteristics of patients with myocarditis were compared with those of AOSD patients without myocarditis.In these 24 myocarditis-complicated AOSD cases, myocarditis occurred early and was present at AOSD onset in 54% of the cases. Myocarditis was often symptomatic (96% of patients) with nonspecific electrocardiographic abnormalities (79% of patients) and a left ventricle ejection fraction ≤50% (67% of patients). Cardiac magnetic resonance imaging and endomyocardial biopsies showed features consistent with myocarditis in 4 patients and a mononuclear interstitial inflammatory infiltrate in 4 others. Steroids alone were effective in 50% of patients with myocarditis. Intravenous immunoglobulins, methotrexate, and tumor necrosis factor-α-blockers were also prescribed and often found effective. Only 1 patient died from cardiogenic shock. Patients with myocarditis-complicated AOSD were younger and more frequently male than patients with AOSD alone. Pericarditis was more frequent in the myocarditis group; white blood cell count, polymorphonuclear cell count, and serum ferritin levels were also higher.Myocarditis is a potentially life-threatening complication of AOSD but responds positively to steroids and other immunomodulatory drugs. Its prognosis remains good (only 1 death occurred), but the condition requires close monitoring of heart function.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.