Evidence map›Paper›PMID 25397434›Full record

ArticleJournal of the International AIDS Society2014

Molecular epidemiology of HIV-1 strains in Antalya, Turkey.

Dilara Inan, Murat Sayan

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

2 authors.

Dilara InanInfectious Diseases and Clinical Microbiology, Faculty of Medicine, Akdeniz University Hospital, Akdeniz University, Antalya, Turkey.
Murat SayanClinical Laboratory, PCR Unit, Kocaeli University Hospital, Kocaeli University, Izmit-Kocaeli, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to determine the subtype distribution of HIV-1 strains isolated from antiretroviral therapy (ART)-naive and on treatment patients in Antalya, the city of southern Turkey. MATERIALS AND

methodsThe study included 77 of 92 newly diagnosed HIV-1 positive patients of last two years (between February 2012 and June 2014). HIV-1 subtypes and circulating recombinant forms (CRFs) were identified by phylogenetic analysis of reverse-transcriptase (codon 41-238) and protease (codon 1-99) domains (~667 bp) of pol gene region in HIV-1 strains.

resultsSubtype B (48%, 37/77) was identified as the most common HIV-1 subtype in Antalya that similar the other Turkish patients. Non-B subtypes were followed as CRFs (39%, 30/77). Interestingly, CRF14_BG (12.9%, 10/77) was found for the first time in Antalya in contrast to previous observations in the other reports in Turkey. Also, subtype G (6.5%, 5/77) was detected more often than HIV-1 subtypes in circulation of Turkey.

conclusionsThese findings may be associated with specific geographic localization of Antalya that touristic movements of city. Recognized HIV-1 subtype diversity is major challenges in the development of a globally effective HIV vaccine.

Identifiers

PMID25397434
PMCPMC4225333

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.