Evidence map›Paper›PMID 25396334›Full record

Trial reportMedicine2014

High-pitch coronary CT angiography at 70 kVp with low contrast medium volume: comparison of 80 and 100 kVp high-pitch protocols.

Long Jiang Zhang, Li Qi, Carlo N De Cecco, Chang Sheng Zhou, James V Spearman, U Joseph Schoepf, Guang Ming Lu

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02971176 (Low-dose Protocol for Computed Tomography-guided Lung Biopsy), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02971176 nacompletednot on this mapstarted 2016, after this paper: background citation

Low-dose Protocol for Computed Tomography-guided Lung Biopsy

TypeinterventionalSponsorXuzhou Central HospitalRan2016 to 2019Enrolled280ConditionsLung Cancer, Adenocarcinoma, Lung Inflammatory PseudotumorArmsLow-dose protocol computed tomography, Standard-dose protocol computed tomography
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  13. Computed tomography in paediatric heart disease.The British journal of radiology · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Long Jiang ZhangDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Li Qi
Carlo N De Cecco
Chang Sheng Zhou
James V Spearman
U Joseph Schoepf
Guang Ming Lu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this article is to evaluate image quality and radiation dose of prospectively electrocardiogram (ECG)-triggered high-pitch coronary computed tomography angiography (CCTA) at 70 kVp and 30 mL contrast medium.One hundred fifty patients with a heart rate ≤70 beats per minute (bpm) underwent CCTA using a second-generation dual-source computed tomography (CT) scanner and were randomized into 3 groups according to tube voltage and contrast medium volume (370 mg/mL iodine concentration) (100 kVp group, 100 kVp/60 mL, n = 55; 80 kVp group, 80 kVp/60 mL, n = 44; 70 kVp group, 70 kVp/30 mL, n = 51). Objective and subjective image quality along with the effect of heart rate (HR) and body mass index (BMI) was evaluated and compared between the groups. Radiation dose was estimated for each patient.CT attenuation and image noise were higher in the 80 and 70 kVp groups than in the 100 kVp group (all P < 0.001). Signal-to-noise ratios (SNRs) and contrast-to-noise ratios (CNRs) were lower in the 70 kVp group than in the 80 and 100 kVp groups (all P < 0.05). There was no difference for subjective image quality between the groups (P > 0.05). HR did not affect subjective image quality (all P > 0.05), while patients with BMI <23 kg/m had higher image quality than patients with BMI ≥23 kg/m (P < 0.05). Compared with the 100 kVp group, the radiation dose of the 70 kVp group was reduced by 75%.In conclusion, prospectively ECG-triggered high-pitch 70 kVp/30 mL CCTA can obtain diagnostic image quality with lower radiation dose in selected patients with BMI <23 kg/m compared with 80/100 kVp/60 mL CCTA.

Indexed as

Contrast MediaCoronary AngiographyElectrocardiographyFemaleHumansMaleMiddle AgedProspective StudiesRadiation DosageTomography, X-Ray ComputedContrast Media

Identifiers

PMID25396334
PMCPMC4616317

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.