Evidence map›Paper›PMID 25396312›Full record

ReviewJournal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer2014

Paraneoplastic disorders in thymoma patients.

Amelia Evoli, Eric Lancaster

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 145 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Thymic central tolerance takes centre stage in autoimmune disease.The Lancet regional health. Western Pacific · 2025
    Article
  9. Article
  10. Mediastinal tumors: why, when, and how to biopsy?Mediastinum (Hong Kong, China) · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Cardiovascular disease in thymic cancer patients.Frontiers in cardiovascular medicine · 2024
    Article
  19. Review
  20. Eculizumab in thymoma-associated myasthenia gravis: a real-world cohort study.Therapeutic advances in neurological disorders · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Amelia Evoli*Department of Neurology, Catholic University, Roma, Italy; and †Department of Neurology, The University of Pennsylvania, Philadelphia, PA.
Eric Lancaster
Università Cattolica del Sacro Cuore · ITUniversity of Pennsylvania · US

Funding

Mechanisms of Caspr2 antibodiesK08NS075142 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI LANCASTER, ERIC · 2012 to 2016
$948k
NINDS NIH HHS K08 NS075142
6 · The paper itself

Abstract

Thymic malignancy is often associated with paraneoplastic neurological diseases (PNDs) and recognition of these disorders is important for physicians who treat these patients. The most common thymoma-associated PNDs are myasthenia gravis (MG), acquired neuromyotonia (Isaacs' syndrome), encephalitis, Morvan's syndrome, and myositis. Diagnosis of these disorders is complex but often aided by testing for specific autoantibodies, including those to the acetylcholine receptor for MG and to contactin-associated protein-like 2, protein of the voltage-gated potassium channel complex, in patients with acquired neuromyotonia, Morvan's syndrome, or encephalitis. Patients who manifest these disorders should be screened for thymoma at diagnosis, and worsening of these PNDs may be associated with recurrent thymoma. These disorders can cause profound disability but usually respond to immunotherapy, and often improve with thymoma treatment. Close cooperation among a team of specialists is required to take proper care of these patients.

Indexed as

HumansParaneoplastic Syndromes, Nervous SystemThymoma

Identifiers

PMID25396312
PMCPMC4234178
OpenAlexW1995401688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.