ArticleJRSM cardiovascular disease2014
Electrocardiogram-based scoring system for predicting secondary pulmonary hypertension: A cross-sectional study.
Article in JRSM cardiovascular disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 3 citations in OpenAlex.
- Improvement in the electrocardiograms associated with right ventricular hypertrophy after balloon pulmonary angioplasty in chronic thromboembolic pulmonary hypertension.International journal of cardiology. Heart & vasculature · 2018Article
- Prevalence and predictive value of electrocardiographic abnormalities in pulmonary hypertension: evidence from the Pan-African Pulmonary Hypertension Cohort (PAPUCO) study.Cardiovascular journal of AfricaArticle
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Authors and funding
8 authors at 1 institution in 1 country.
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Abstract
objectivesIn this study, we have developed an electrocardiogram-based scoring system to predict secondary pulmonary hypertension.
designA cross-sectional study.
settingSingle tertiary-care hospital in Scranton, Pennsylvania, USA.
participantsFive hundred and fifty-two consecutive patients undergoing right heart catheterization between 2006 and 2009.
main outcome measuresSurface electrocardiogram was assessed for R-wave in lead V1 ≥ 6mm, R-wave in V6 ≤ 3mm, S-wave in V6 ≥ 3mm, right atrial enlargement, right axis deviation and left atrial enlargement. Pulmonary hypertension was defined as mean pulmonary artery pressure ≥25 mmHg, determined by right heart catheterization.
resultsA total of 297 (54%) patients in the study cohort had pulmonary hypertension. In total, 332 patients from the study cohort formed the development cohort and the remaining 220 patients formed the validation cohort. In the development cohort, based on log odds ratios of association, RAE, LAE, RAD, R-wave in V1 ≥ 6 mm were assigned scores of 5, 2, 2 and 1, respectively, to form a 10-point scoring system "Scranton PHT (SP) score". SP scores of 5 points and 7 points in DC showed C-statistic of 0.83 and 0.89, respectively, for discriminating pulmonary hypertension. C-statistic for RAE alone was significantly lower compared to an SP score of 7 (0.83 vs. 0.89, P = 0.021). The reliability of SP score in the validation cohort was acceptable.
conclusionSP score provides a good point-of-care tool to predict pulmonary hypertension in patients with clinical suspicion of it.
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