Evidence map›Paper›PMID 25396041›Full record

ArticleChemical science2014

Synthesis of diarylmethylamines

Minyan Li, Baris Yücel, Javier Adrio, Ana Bellomo, Patrick J Walsh

Abstract read
In one paragraph

Article in Chemical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. α-C-H Functionalization of Benzylamines: A Crucial Yet Challenging Transformation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. EnantioselectiveACS omega · 2020
    Article
  11. One Amine-3 Tasks: Reductive Coupling of Imines with Olefins in Batch and Flow.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  12. Article
  13. 2-Azadienes as Enamine Umpolung Synthons for the Preparation of Chiral Amines.Synlett : accounts and rapid communications in synthetic organic chemistry · 2019
    Article
  14. Article
  15. Article
  16. Control of chemoselectivity in asymmetric tandem reactions: Direct synthesis of chiral amines bearing nonadjacent stereocenters.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  17. Article
  18. Article
  19. Transition-Metal-Free Radical C(spJournal of the American Chemical Society · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Minyan LiDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA. Web: http://titanium.chem.upenn.edu/walsh/index.html.
Baris YücelDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA. Web: http://titanium.chem.upenn.edu/walsh/index.html ; Istanbul Technical University, Department of Chemistry, 34469 Maslak, Istanbul, Turkey.
Javier AdrioDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA. Web: http://titanium.chem.upenn.edu/walsh/index.html ; Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Química Organica, Cantoblanco, 28049 Madrid, Spain.
Ana BellomoDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA. Web: http://titanium.chem.upenn.edu/walsh/index.html.
Patrick J WalshDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA. Web: http://titanium.chem.upenn.edu/walsh/index.html.

Funding

Arylation of weakly acidic sp3 hybridized C-H'sR01GM104349 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI WALSH, PATRICK J · 2013 to 2016
$1.3M
NIGMS NIH HHS R01 GM104349
6 · The paper itself

Abstract

Diarylmethylamines are of great interest due to their prevalence in pharmaceutical chemistry. As a result, new methods for their synthesis are in demand. Herein, we report a versatile protocol for the synthesis of diarylmethylamine derivatives involving palladium-catalyzed arylation of

Identifiers

PMID25396041
PMCPMC4225812

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.