Evidence map›Paper›PMID 25395935›Full record

ReviewArchives of medical science : AMS2014

The incidence of acute myocardial infarction in relation to overweight and obesity: a meta-analysis.

Jun Zhu, Xiaohua Su, Gang Li, Jingsong Chen, Bing Tang, Yongjian Yang

Open access · goldAbstract readReview
In one paragraph

Review in Archives of medical science : AMS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
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  4. Observational
  5. Combined Oral Contraceptives and the Risk of Thrombosis.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jun ZhuDepartment of Cardiology, General Hospital of PLA, Chengdu Military Area Command, Tianhui Town, Jinniu District, Chengdu, China.
Xiaohua SuDepartment of Cardiology, General Hospital of PLA, Chengdu Military Area Command, Tianhui Town, Jinniu District, Chengdu, China.
Gang LiDepartment of Cardiology, General Hospital of PLA, Chengdu Military Area Command, Tianhui Town, Jinniu District, Chengdu, China.
Jingsong ChenDepartment of Cardiology, General Hospital of PLA, Chengdu Military Area Command, Tianhui Town, Jinniu District, Chengdu, China.
Bing TangDepartment of Cardiology, General Hospital of PLA, Chengdu Military Area Command, Tianhui Town, Jinniu District, Chengdu, China.
Yongjian YangDepartment of Cardiology, General Hospital of PLA, Chengdu Military Area Command, Tianhui Town, Jinniu District, Chengdu, China.
Chengdu Military General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEpidemiological evidence suggests that overweight and obesity have been associated with acute myocardial infarction (AMI). However, data on this issue are controversial. This study aims to use meta-analysis to determine whether overweight and obesity are related to AMI. MATERIAL AND

methodsWe searched PubMed and Embase databases up to October 23(rd), 2013 for related literature. The association of overweight and obesity with AMI was assessed by odd ratio (OR) with 95% confidence interval (CI) as the effect size. Then subgroup analysis was performed according to gender, area and study type.

resultsFive primary studies (one cohort study and four case-control studies) were included in this meta-analysis involving 36 803 participants, 14 883 of whom had an AMI. There was a significant association between overweight and AMI (OR = 1.27, 95% CI: 1.21-1.33, p < 0.001). Similar results revealed a relation between obesity and AMI (OR = 1.22, 95% CI: 1.07-1.40, p = 0.003). Subgroup analysis showed that overweight and obesity were positively associated with AMI risk except for obese subjects in Europe. There was no publication bias (Begg's test p = 0.972, Egger's test p = 0.858).

conclusionsBoth overweight and obesity increased the incidence of AMI, and it is necessary to control weight to prevent AMI. A large number of studies is needed to explore the mechanisms that link overweight and obesity with AMI.

Indexed as

acute myocardial infarctionmeta-analysisobesityoverweight

Identifiers

PMID25395935
PMCPMC4223131
OpenAlexW145046761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.