Evidence map›Paper›PMID 25395912›Full record

ArticleJournal of health, population, and nutrition2014

Urban-rural differences in atherogenic dyslipidaemia (URDAD Study): a retrospective report on diabetic and non-diabetic subjects of Northern India.

Poonam Agrawal, Varikasuvu Seshadri Reddy, Himanshu Madaan, Surajeet Kumar Patra, Renu Garg

Open access · greenAbstract read
In one paragraph

Article in Journal of health, population, and nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Poonam AgrawalDepartment of Biochemistry, BPS Government Medical College for Women, Khanpur Kalan, Sonepat, Haryana, India.
Varikasuvu Seshadri ReddyDepartment of Biochemistry, BPS Government Medical College for Women, Khanpur Kalan, Sonepat, Haryana, India.
Himanshu MadaanDepartment of Biochemistry, BPS Government Medical College for Women, Khanpur Kalan, Sonepat, Haryana, India.
Surajeet Kumar PatraDepartment of Biochemistry, Lady Hardinge Medical College, Delhi, India.
Renu GargDepartment of Biochemistry, BPS Government Medical College for Women, Khanpur Kalan, Sonepat, Haryana, India.
Government Medical College · INLady Hardinge Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes and urbanization are major contributors to increased risk factors of cardiovascular diseases. Studying whether atherogenic dyslipidaemia increases with urbanization in type 2 diabetes mellitus is, therefore, important. The sample of the present study consisted of 400 subjects. They were categorized according to residential area and diabetes into four groups: urban diabetic group, urban non-diabetic control group (from a metropolitan city Delhi), rural non-diabetic diabetic group, and rural control group (from villages of Khanpur Kalan, Sonepat, Haryana). Differences in lipid levels and risk factors of emerging cardiovascular diseases between groups were evaluated with analysis of variance. Diabetic patients of both urban and rural areas had significantly higher total cholesterol (TC), triglycerides (TG), very low-density lipoproteins (VLDL), TC to high-density lipoprotein cholesterol (TC/HDL) ratio, TG to high-density lipoprotein cholesterol (TG/HDL) ratio, and atherogenic index (AI) compared to respective controls (p<0.05). The HDL concentrations in urban diabetics were significantly lower (p<0.05) than in urban non-diabetic group and rural diabetic group. Comparison between urban and rural diabetic groups showed significantly higher atherogenic dyslipidaemia (AD) in the urban patient-group (p<0.05). We evaluated significant relationships of diabetes and urbanization with AD by multiple regression analysis. Receiver operating curve (ROC) analysis showed high area under curve (AUC) for TG/HDL in urban diabetic group (0.776, p<0.0001) and in rural diabetic group (0.692, p<0.0001). It is concluded that diabetes was associated with higher AD parameters. Urbanization in diabetes is also associated with elevated levels of AD, indicating higher risk in urban population. This study suggests that TG/HDL may be particularly useful as atherogenic risk predictor in newly-diagnosed type 2 diabetic patients.

Indexed as

AdultAtherosclerosisCardiovascular DiseasesCholesterol, HDLDiabetes Mellitus, Type 2DyslipidemiasFemaleGeography, MedicalHumansIndiaMaleMiddle AgedRetrospective StudiesRisk FactorsRural PopulationUrban PopulationCholesterol, HDLAtherogenic dyslipidaemiaAtherogenic indexDiabetesIndiaUrbanization

Identifiers

PMID25395912
PMCPMC4221455
OpenAlexW1921631969

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.